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Implementation of an Integrated, Clinical Decision Support Tool at the Point of Antihypertensive Medication Refill Request to Improve Hypertension Management: Controlled Pre-Post Study

Implementation of an Integrated, Clinical Decision Support Tool at the Point of Antihypertensive Medication Refill Request to Improve Hypertension Management: Controlled Pre-Post Study

Hypertension, the most common chronic condition treated in primary care [7], has shown that EHR-integrated applications, as described by Funes et al [8], can improve clinician workflows in chronic disease management. In addition, the American Heart Association and the American Medical Association have called upon primary care teams to better leverage protocols and team-based care to improve hypertension control [9].

John Charles Matulis 3rd, Jason Greenwood, Michele Eberle, Benjamin Anderson, David Blair, Rajeev Chaudhry

JMIR Med Inform 2025;13:e70752

Maternal Metabolic Health and Mother and Baby Health Outcomes (MAMBO): Protocol of a Prospective Observational Study

Maternal Metabolic Health and Mother and Baby Health Outcomes (MAMBO): Protocol of a Prospective Observational Study

The offspring of mothers with pre-existing metabolic diseases—obesity, diabetes, and hypertension—have an increased risk of significant congenital anomalies and premature birth compared with the offspring of mothers without metabolic disease [1]. These offspring are also twice as likely to develop obesity, diabetes, and hypertension in childhood [2].

Sarah A L Price, Digsu N Koye, Alice Lewin, Alison Nankervis, Stefan C Kane

JMIR Res Protoc 2025;14:e72542

Effect of Continuous Positive Airway Pressure or Positional Therapy Compared to Control for Treatment of  Obstructive Sleep Apnea on the Development of Gestational Diabetes Mellitus in Pregnancy: Protocol for Feasibility Randomized Controlled Trial

Effect of Continuous Positive Airway Pressure or Positional Therapy Compared to Control for Treatment of Obstructive Sleep Apnea on the Development of Gestational Diabetes Mellitus in Pregnancy: Protocol for Feasibility Randomized Controlled Trial

The authors report risk reduction of gestational hypertension and preeclampsia in the CPAP groups (relative risk [RR] 0.65, 95% CI 0.47-0.89; P=.008) and preeclampsia (RR 0.70, 95% CI 0.50-0.98; P=.04), which were not correlated with age or BMI. The authors concluded that while the results suggest CPAP therapy as a potential mediator to adverse gestational hypertensive outcomes in pregnant women with OSA, the association remains inconclusive [40].

Frances Clements, Hima Vedam, Yewon Chung, John Smoleniec, Colin Sullivan, Renuka Shanmugalingam, Annemarie Hennessy, Angela Makris

JMIR Res Protoc 2025;14:e51434

Appropriateness of Web-Based Resources for Home Blood Pressure Measurement and Their Alignment With Guideline Recommendations, Readability, and End User Involvement: Environmental Scan of Web-Based Resources

Appropriateness of Web-Based Resources for Home Blood Pressure Measurement and Their Alignment With Guideline Recommendations, Readability, and End User Involvement: Environmental Scan of Web-Based Resources

High blood pressure (BP; hypertension: BP≥140/90 mm Hg) is the leading risk factor for death worldwide [1,2]. High BP can be controlled ( In the absence of effective in-clinic education and with the increased use of telehealth, web-based resources are commonly used by adults who seek health-related information for self-education [13]. In addition, recent work in Australia has shown that >35% of adults would prefer to access information about high BP on the web [14].

Eleanor Clapham, Dean Picone, Samuel Carmichael, Carissa Bonner, Niamh Chapman

JMIR Infodemiology 2025;5:e55248

Insights Into How mHealth Applications Could Be Introduced Into Standard Hypertension Care in Germany: Qualitative Study With German Cardiologists and General Practitioners

Insights Into How mHealth Applications Could Be Introduced Into Standard Hypertension Care in Germany: Qualitative Study With German Cardiologists and General Practitioners

Advancing digitalization of health care has a transformative impact on the prevention and treatment of diseases, particularly in the realm of hypertension. In this context, mobile health (m Health) apps are increasingly gaining significance, offering innovative means for monitoring, maintaining, and preventing high blood pressure [1-3]. Hypertension poses a substantial health challenge, affecting millions of people worldwide [4].

Susann May, Frances Seifert, Dunja Bruch, Martin Heinze, Sebastian Spethmann, Felix Muehlensiepen

JMIR Mhealth Uhealth 2025;13:e56666

Stress and Hypertension Among African American Female Family Caregivers of Persons Living With Alzheimer Disease and Related Dementias: Protocol for a Pilot Internet-Based Randomized Controlled Trial

Stress and Hypertension Among African American Female Family Caregivers of Persons Living With Alzheimer Disease and Related Dementias: Protocol for a Pilot Internet-Based Randomized Controlled Trial

No demographic group is more at risk for the double jeopardy of caregiving stress and hypertension than African American women caring for a family member who has ADRD. Hypertension is the leading cause of cardiovascular disease among African American women, affecting 56.7% of this group [8].

Kathy D Wright, Ingrid K Richards Adams, Nathan P Helsabeck, Karen M Rose, Karen O Moss, Donya Nemati, Navia Palmer, Bohyun Kim, Sunita Pokhrel Bhattarai, Christopher Nguyen, Daniel Addison, Maryanna D Klatt

JMIR Res Protoc 2025;14:e66975

Factors Influencing Primary Care Physicians’ Intent to Refer Patients With Hypertension to a Digital Remote Blood Pressure Monitoring Program: Mixed Methods Study

Factors Influencing Primary Care Physicians’ Intent to Refer Patients With Hypertension to a Digital Remote Blood Pressure Monitoring Program: Mixed Methods Study

Hypertension is a leading independent and modifiable risk factor for several adverse cardiovascular outcomes including coronary artery disease, stroke, heart failure, and chronic kidney disease, as well as a wide variety of mental and metabolic conditions [1]. Long-term control of hypertension can be achieved through proven interventions including regular blood pressure (BP) monitoring [2]. Accurate BP measurements in the office can be a challenge, particularly if the patient has white coat syndrome [3].

Jennifer J Wu, Ross Graham, Julie Çelebi, Kevin Fraser, Geneen T Gin, Laurel Dang, Esmatullah Hatamy, Amanda Walker, Courtney Barbato, Ottar Lunde, Lisa Coles, Parag Agnihotri, Cassandra Morn, Ming Tai-Seale

J Med Internet Res 2025;27:e64933

Two-Year Hypertension Incidence Risk Prediction in Populations in the Desert Regions of Northwest China: Prospective Cohort Study

Two-Year Hypertension Incidence Risk Prediction in Populations in the Desert Regions of Northwest China: Prospective Cohort Study

Hypertension, a major preventable risk factor for cardiovascular disease, accounts for approximately 50% of all cardiovascular-related deaths globally [2]. In China, the prevalence of hypertension has been rising due to rapid urbanization, increasing affluence, and an aging population. Recent surveys estimate that approximately 244.5 million Chinese adults (23.2%) are affected by hypertension, with this number continuing to increase [3,4].

Yinlin Cheng, Kuiying Gu, Weidong Ji, Zhensheng Hu, Yining Yang, Yi Zhou

J Med Internet Res 2025;27:e68442

Benefits and Barriers to mHealth in Hypertension Care: Qualitative Study With German Health Care Professionals

Benefits and Barriers to mHealth in Hypertension Care: Qualitative Study With German Health Care Professionals

Hypertension is a significant health problem affecting millions of people worldwide [1]. In Germany, too, hypertension is one of the most common diseases affecting a large proportion of the population. Prevention and effective treatment of hypertension are therefore crucial to prevent associated serious complications such as ischemic heart disease, strokes, and renal disease, and to improve the quality of life of those affected [2-4].

Susann May, Felix Muehlensiepen, Eileen Wengemuth, Frances Seifert, Martin Heinze, Dunja Bruch, Sebastian Spethmann

JMIR Hum Factors 2025;12:e52544

Health Equity of Hypertension Management Between Local Residents and Internal Migrants in Shenzhen, China: Cross-Sectional Study

Health Equity of Hypertension Management Between Local Residents and Internal Migrants in Shenzhen, China: Cross-Sectional Study

The World Health Organization’s latest report highlights a surge in hypertension prevalence, with figures doubling from 650 million individuals in 1990 to an alarming 1.3 billion in 2019 [2]. In China, about 270 million people have hypertension, while research showed that, among the 256 million individuals aged 30-79 years with hypertension, only 52% were aware of their condition, 39% were receiving treatment, and a scant 16% had their blood pressure under control [2,3].

Jinyu He, Yanjun Li, Huatang Zeng, Haoran Sun, Liqun Wu, Zhenzhen Zhu, Ning Zhang, Wannian Liang

JMIR Public Health Surveill 2025;11:e65548