This cross-sectional website analysis was designed to evaluate the reliability and quality of Arabic online information about DR. Google.com, the most widely used search engine worldwide, held a 90.29% market share in Asia and a 97.19% market share in Africa as of May 2024. Arabic-speaking countries in the Middle East span both continents. For example, Saudi Arabia has a market share of 95.60% while Egypt has 97.38% [9]. The engine was used on May 1, 2024, to search for the Arabic term for DR, “اعتلال الشبكية السكري,” in incognito mode using a new account to avoid browser bias. The first 100 search results were examined, simulating a patient’s or a general reader’s search behavior.

Websites were included if they were written primarily in Arabic and focused on providing educational content about DR for patients or the general public. Eligible websites were required to contain written text that addressed DR-specific topics, such as causes, symptoms, diagnosis, treatment options, and preventive strategies. The inclusion was limited to the first 100 search results to reflect typical patient behavior when searching for online health information.

Websites were excluded if they were not written in Arabic, targeted health care professionals (such as academic articles or clinical guidelines), or consisted solely of multimedia content like videos or audio recordings without accompanying text. In addition, websites that required login credentials, subscription access, or were otherwise inaccessible were excluded. Duplicate URLs among the first 100 search results were also removed. Finally, websites with irrelevant content, such as general diabetes pages lacking specific focus on DR, social media posts, news articles, blogs, forums, or advertisements, were excluded. The searching process is further illustrated in Figure 1.

Table 1 exhibits the list of websites eligible for evaluation. Some websites, such as Mayo Clinic, have identical URLs in different languages but automatically localize content to Arabic. Websites were classified into four main categories: hospitals and medical centers, health portals (websites dedicated to health information), commercial (websites selling a service or product), and nonprofit organizations.

The evaluation was performed by 2 independent raters (Evaluators A and B), followed by a shared revision session to determine a final rating and resolve any disagreements from the initial evaluation. The 2 raters were senior medical students trained in the use of the DISCERN and JAMA benchmarks, following a structured protocol to ensure consistency and objectivity. While not board-certified ophthalmologists, the raters applied the tools according to standardized instructions that do not require clinical expertise. Raters followed the instructions of the tools to objectively determine appropriate scores for each website. The final rating was derived from the initial independent evaluations and did not substantially deviate from either rater’s original score. In all instances, the final rating either corresponded to one of the initial assessments or reflected a minor adjustment reached through consensus during the revision session.

All data was organized in an Excel (Microsoft) spreadsheet and imported into IBM SPSS (version 21; IBM Corp). Descriptive statistics, such as means and SDs, were used to summarize website characteristics and evaluation scores. Normality tests were conducted to determine the data distribution (normal or nonparametric), and appropriate statistical tests were applied. Because internet users are more likely to view websites on the first page of Google (the first 10 websites) [42], these were considered to be the most viewed and therefore grouped together to be compared with the websites of other pages using both the Mann-Whitney U test and independent 2-tailed t test according to the distribution of the data. The direction of association between the DISCERN and JAMA scores was examined using nonparametric measures, more specifically Spearman rank correlation. A P value below .05 was considered statistically significant. This study was reported in accordance with the STROBE (Strengthening the Reporting of Observational Studies in Epidemiology) guidelines [43].

Our search for the Arabic term for DR using the Google search engine yielded 178,000 websites. Examining the first 100 revealed 13 duplicates, which were excluded, and further filtering of the remaining 87 for eligibility led to the exclusion of pages in languages other than Arabic, video or audio content only, inaccessible sites requiring visitors to sign in, those targeting medical professionals only, irrelevant topics, advertisements, social media posts, and news reports. Among the 30 pages that were eligible for further analysis, one more website was excluded and removed from the dataset as it became unavailable during the analysis process.

Of the 29 websites finally included, the majority (n=20, 69%) were classified as hospitals and medical centers. Commercial pages made up 4 (13.8%) websites. Around 3 (10.3%) websites fell under the health portal classification. The remaining 2 (6.9%) websites belonged to the foundation or nonprofit organization category.

The overall mean score of DISCERN for all websites was low (mean 36.59,SD 9.322), ranging from 17 to 61 points. None of the websites reached the “excellent” category (≥63 points). Only 2 of 29 (6.9%) websites scored in the “good” range (≥51 points). A total of 7 of 29 (24.1%) pages fell into the “average” category with a score ranging from 39 to 50 points. The majority of the included websites (16/29, 55.2%) had a “poor” score (38‐28 points), and the remaining 4 of 29 (13.8%) pages achieved a “very poor” score of less than 28 points.

The overall quality score (DISCERN item 16) of the identified 29 websites had an average of 2.45 (SD 0.910). The DISCERN items with the highest scores were related to the relevancy of the content, the variety of treatment options, and how each treatment works (mean 4.59, SD 0.983; mean 4.00, SD 1.000; and mean 4.10, SD 1.263, respectively; Table 2).

Several websites scored low in relation to revealing the explicit aims of their content and their source of information (mean 1.38,SD 1.015 and mean 1.45, SD 1.055, respectively). In addition, not many pages reported the date their content was created or published (mean score 1.48, SD 0.949). Few websites mentioned the possible risks of each treatment (mean score 1.90, SD 1.345), and almost none of the websites (1/29, 3.4%) highlighted any “gray” areas or uncertainties about the outcomes of the treatments (mean score 1.10, SD 0.557). Nearly all websites (27/29, 93.1%) scored 1 point out of 5 in the question related to the effect of treatment on quality of life (mean 1.17, SD 0.658; Table 2).

None of the websites obtained a score higher than 2 on the JAMA benchmarks tool (mean 0.45, SD 0.632), placing them all in the “low reliability” category. Over two-thirds (18/29, 62.1%) of the websites failed to meet any criteria, while the remaining websites (11/29, 37.9%) met only 1 or 2. The most common criterion met was currency, with 10 of 29 (34.5%) websites complying with it and an average score of 0.34 (SD 0.484). Authorship (mean 0.03, SD 0.186) and disclosure (mean 0.07, SD 0.258) were only displayed on 1 and 2 web pages (1/29, 3.4% and 2/29, 6.9%, respectively). No website has fulfilled the attribution benchmark. A very weak positive correlation between the DISCERN and JAMA scores was observed (ρ=0.130; P=.50).

Out of 20 questions, a single website (1/29, 3.4%) answered the most, covering 75% of the questions. On the other hand, (2/29, 6.9% of the group) websites answered the least number of questions, only covering 15%. While most websites (27/29, 93.1%) explained what DR was and how it was treated, very few mentioned the screening period for DR (8/29, 27.6%). Only 2 of 29 (6.9%) websites discussed the reversibility of vision loss caused by DR. Moreover, 5 of 29 (17.2%) of the included websites covered the surgical options to treat DR and its possible risks. The vast majority (25/29, 86.2%) lacked images of DR (Table 3).

The Mann-Whitney U test revealed no significant difference in JAMA scores between the first 10 websites (displayed on the first page) and those on subsequent pages (1-tailed P=.12). Similarly, bivariate analysis showed no significant difference in the DISCERN and content scores between the websites of the first page and other pages (P=.72). Detailed individual website scores for quality, reliability, and content are presented in Table 4.

Our study assessed the reliability and quality of the contents of 29 Arabic websites covering DR based on DISCERN and JAMA benchmarks. Using the DISCERN tool to evaluate the quality of each website has shown an overall poor quality of all websites evaluated, with an average score of 36.59 (SD 9.322). None of the 29 websites assessed achieved “excellent,” with the majority of the websites falling under the “poor” (16/29, 55.2%) and “very poor” (4/29, 13.8%) categories. The content of the websites seems to falter in the first section of the DISCERN instrument focusing on the trustworthiness of the content presented (questions 1‐8), which reflects the unreliability of the websites offering information on DR in Arabic. In addition, comprehensive reporting of treatment options with their associated benefits and risks was inconsistent between the websites, compromising the overall quality of the content presented. Our study found that the average score of the overall quality on the DISCERN tool is 2.45 (SD 0.9), which falls under the category of having “potentially important but not serious shortcomings.” This outcome is similar to the results found by Novin et al [40], who evaluated the information about DR on US-based online websites and observed a mean score of 2.09 (SD 0.594), and similar to our results, no website was classified as “excellent” in their analysis. Moreover, both studies observed a deficiency in directing the readers to discuss their conditions with their physicians. While a perfect score of 5 signifies the highest quality, none of the analyzed websites achieved this benchmark.

Given the consistently poor quality and reliability scores across websites, these findings may be explained by several underlying factors. Hypotheses include (1) the absence of standardized quality controls in Arabic web content, (2) limited contributions from medical institutions in developing and maintaining patient education resources, and (3) a general lack of regulatory oversight governing the accuracy and reliability of health information published online. Such systemic gaps likely underlie the consistently low quality and reliability scores observed in our assessment.

Similar to the DISCERN assessment of the websites, assessing the 29 websites included with the JAMA benchmarks tool has revealed that all the websites are of low reliability. None of the websites evaluated obtained a score higher than 2, with an average score of 0.45 (SD 0.632). Comparing our results to the study done on dry eye disease websites, their assessment using JAMA has found that all the websites failed to meet half the benchmarks as well, with an average of 1.9 (SD 0.1) [44]. The low average in our study is due to more than two-thirds (18/29, 62.1%) of the websites assessed failing to meet any of the 4 JAMA benchmark criteria for a reliable website. A study conducted by Kloosterboer et al [6] on assessing online information regarding DR has also found that none of the websites evaluated has achieved all 4 JAMA benchmarks.

Upon evaluating each website’s content, it was observed that no website has covered all questions, with the highest-scoring website only fulfilling 75% of the questions (n=15). While most websites included information on what DR is and how it is treated, many of them (20/29, 69%) lacked information about when screening should begin. The study by Novin et al [6] also noted this, pointing out that there was insufficient content on the DR screening intervals for type 1 and type 2 diabetes. A substantial number of the evaluated websites did not thoroughly address every therapeutic choice with its correlated risks and benefits. This was also a common finding in another study assessing DR-related internet resources for patients, where most websites scored in the lower range in questions related to treatment options.

The study found the average score for the balance and unbiasedness item of the DISCERN instrument to be 3.62 (SD 1.24) for Arabic websites covering DR. This rating may be attributed to the inclusion of commercial websites in the evaluation, despite excluding those explicitly labeled as “advertisement” or “ad” in Google search results. These commercial sites, while offering health services or products, also provide health educational content. The presence of commercial links and advertisements can hinder users’ ability to locate reliable information, contributing to a “misinfodemic” and making it challenging for patients to access trustworthy health resources [45].

We believe that the gap found in the quality of content reported on all the assessed websites reflects the current health care practices in the region, where collaborative decision-making and thorough explanation of treatment risks and benefits may not always be given priority. A systematic literature review of patient-centered care (PCC) in the Middle East concluded that while there is support for adopting PCC in the Middle East and North African region, its implementation is still limited [46]. Webair identified barriers to adopting a PCC approach at multiple levels, mostly related to communication, suggesting a preference for a physician-driven approach that may not place as much emphasis on discussing treatment alternatives with patients [47].

Our study has its own set of limitations that require addressing for future investigation and research. First, Google was the primary search engine used in this study. Although it is a well-renowned and widely used search engine, the use of other search engines could provide more websites that were not taken into consideration by relying solely on Google [9]. The second limitation is the exclusive focus on written Arabic-language content. Video-based or multimedia educational resources, which are increasingly used by patients, were excluded from this analysis. Evaluating such content could provide further insights into the quality of health information consumed by the general population through popular platforms, such as WhatsApp (Meta Platforms Inc), YouTube (Google), or TikTok (ByteDance). While the quality of the content was assessed thoroughly in our study, assessing the readability of the websites included could provide insight into whether the information provided can be adequately comprehended by patients or not. Further studies should be performed in this area to assess whether websites are within the acceptable reading levels of online educational materials.

The study shows the need to improve the quality and reliability of Arabic-language online content on DR. Content creators should follow best practices in health communication, including clear authorship, proper source attribution, transparency regarding sponsorship, and regular content updates. Information should also be patient-centered, discussing treatment options, associated risks, and preventive measures like regular screening.

At the policy level, national guidelines are needed to ensure the quality of Arabic online health information. Policymakers may consider implementing standardized accreditation systems like the Health on the Net Code of Conduct, adapted to the region’s linguistic and cultural context, to combat misinformation and enhance public health literacy.

Our study’s findings disclose that Arabic-language websites providing information on DR treatment are significantly deficient in quality, reliability, and content. The DISCERN assessment tool displayed a “poor” score for most of the analyzed websites (16/29, 55.2%). In addition, according to the JAMA benchmark criteria, all of the websites showed low reliability, and none of them met the attribution benchmark. These findings highlight the necessity of enhancing the Arabic-language websites discussing DR treatment due to the high prevalence of this condition among patients in the Middle East and the insufficient high-quality online resources available. Middle Eastern health care organizations should collaborate to provide reliable, evidence-based online resources addressing this serious condition. While most websites discuss the treatment of DR, more information is needed on the associated risks and benefits, as well as a stronger focus on joint decision-making. In addition, Arabic websites should encourage screening and preventive measures to enhance patient outcomes.