<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD Journal Publishing DTD v2.0 20040830//EN" "http://dtd.nlm.nih.gov/publishing/2.0/journalpublishing.dtd">
<article article-type="research-article" dtd-version="2.0" xmlns:xlink="http://www.w3.org/1999/xlink">
  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JI</journal-id>
      <journal-id journal-id-type="nlm-ta">JMIR Infodemiology</journal-id>
      <journal-title>JMIR Infodemiology</journal-title>
      <issn pub-type="epub">2564-1891</issn>
      <publisher>
        <publisher-name>JMIR Publications</publisher-name>
        <publisher-loc>Toronto, Canada</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">v3i1e43001</article-id>
      <article-id pub-id-type="pmid"/>
      <article-id pub-id-type="doi">10.2196/43001</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Original Paper</subject>
        </subj-group>
        <subj-group subj-group-type="article-type">
          <subject>Original Paper</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>The Quality, Readability, and Accuracy of the Information on Google About Cannabis and Driving: Quantitative Content Analysis</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="editor">
          <name>
            <surname>Baur</surname>
            <given-names>Cynthia</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Zelaya</surname>
            <given-names>Carina</given-names>
          </name>
        </contrib>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Lamy</surname>
            <given-names>Francois</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib id="contrib1" contrib-type="author">
          <name name-style="western">
            <surname>Josey</surname>
            <given-names>Maria</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0009-0001-3155-4570</ext-link>
        </contrib>
        <contrib id="contrib2" contrib-type="author">
          <name name-style="western">
            <surname>Gaid</surname>
            <given-names>Dina</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-3419-941X</ext-link>
        </contrib>
        <contrib id="contrib3" contrib-type="author">
          <name name-style="western">
            <surname>Bishop</surname>
            <given-names>Lisa D</given-names>
          </name>
          <degrees>PharmD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-4979-4222</ext-link>
        </contrib>
        <contrib id="contrib4" contrib-type="author">
          <name name-style="western">
            <surname>Blackwood</surname>
            <given-names>Michael</given-names>
          </name>
          <degrees>BSc</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-9345-7074</ext-link>
        </contrib>
        <contrib id="contrib5" contrib-type="author">
          <name name-style="western">
            <surname>Najafizada</surname>
            <given-names>Maisam</given-names>
          </name>
          <degrees>MD, PhD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-9195-5379</ext-link>
        </contrib>
        <contrib id="contrib6" contrib-type="author" corresp="yes" equal-contrib="yes">
          <name name-style="western">
            <surname>Donnan</surname>
            <given-names>Jennifer R</given-names>
          </name>
          <degrees>PhD, MBA</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <address>
            <institution>School of Pharmacy, Memorial University of Newfoundland</institution>
            <addr-line>300 Prince Philip Drive</addr-line>
            <addr-line>St. John's, NL, A1B 3V6</addr-line>
            <country>Canada</country>
            <phone>1 709 864 3587</phone>
            <email>jennifer.donnan@mun.ca</email>
          </address>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-2908-0804</ext-link>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <label>1</label>
        <institution>School of Pharmacy, Memorial University of Newfoundland</institution>
        <addr-line>St. John's, NL</addr-line>
        <country>Canada</country>
      </aff>
      <author-notes>
        <corresp>Corresponding Author: Jennifer R Donnan <email>jennifer.donnan@mun.ca</email></corresp>
      </author-notes>
      <pub-date pub-type="collection">
        <year>2023</year>
      </pub-date>
      <pub-date pub-type="epub">
        <day>2</day>
        <month>5</month>
        <year>2023</year>
      </pub-date>
      <volume>3</volume>
      <elocation-id>e43001</elocation-id>
      <history>
        <date date-type="received">
          <day>27</day>
          <month>9</month>
          <year>2022</year>
        </date>
        <date date-type="rev-request">
          <day>12</day>
          <month>12</month>
          <year>2022</year>
        </date>
        <date date-type="rev-recd">
          <day>6</day>
          <month>2</month>
          <year>2023</year>
        </date>
        <date date-type="accepted">
          <day>25</day>
          <month>3</month>
          <year>2023</year>
        </date>
      </history>
      <copyright-statement>©Maria Josey, Dina Gaid, Lisa D Bishop, Michael Blackwood, Maisam Najafizada, Jennifer R Donnan. Originally published in JMIR Infodemiology (https://infodemiology.jmir.org), 02.05.2023.</copyright-statement>
      <copyright-year>2023</copyright-year>
      <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
        <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Infodemiology, is properly cited. The complete bibliographic information, a link to the original publication on https://infodemiology.jmir.org/, as well as this copyright and license information must be included.</p>
      </license>
      <self-uri xlink:href="https://infodemiology.jmir.org/2023/1/e43001" xlink:type="simple"/>
      <abstract>
        <sec sec-type="background">
          <title>Background</title>
          <p>The public perception of driving under the influence of cannabis (DUIC) is not consistent with current evidence. The internet is an influential source of information available for people to find information about cannabis.</p>
        </sec>
        <sec sec-type="objective">
          <title>Objective</title>
          <p>The purpose of this study was to assess the quality, readability, and accuracy of the information about DUIC found on the internet using the Google Canada search engine.</p>
        </sec>
        <sec sec-type="methods">
          <title>Methods</title>
          <p>A quantitative content analysis of the top Google search web pages was conducted to analyze the information available to the public about DUIC. Google searches were performed using keywords, and the first 20 pages were selected. Web pages or web-based resources were eligible if they had text on cannabis and driving in English. We assessed (1) the quality of information using the Quality Evaluation Scoring Tool (QUEST) and the presence of the Health on the Net (HON) code; (2) the readability of information using the Gunning Fox Index (GFI), Flesch Reading Ease Scale (FRES), Flesch-Kincaid Grade Level (FKGL), and Simple Measure of Gobbledygook (SMOG) scores; and (3) the accuracy of information pertaining to the effects of cannabis consumption, prevalence of DUIC, DUIC effects on driving ability, risk of collision, and detection by law enforcement using an adapted version of the 5Cs website evaluation tool.</p>
        </sec>
        <sec sec-type="results">
          <title>Results</title>
          <p>A total of 82 web pages were included in the data analysis. The average QUEST score was 17.4 (SD 5.6) out of 28. The average readability scores were 9.7 (SD 2.3) for FKGL, 11.4 (SD 2.9) for GFI, 12.2 (SD 1.9) for SMOG index, and 49.9 (SD 12.3) for FRES. The readability scores demonstrated that 8 (9.8%) to 16 (19.5%) web pages were considered readable by the public. The accuracy results showed that of the web pages that presented information on each key topic, 96% (22/23) of them were accurate about the effects of cannabis consumption; 97% (30/31) were accurate about the prevalence of DUIC; 92% (49/53) were accurate about the DUIC effects on driving ability; 80% (41/51) were accurate about the risk of collision; and 71% (35/49) were accurate about detection by law enforcement.</p>
        </sec>
        <sec sec-type="conclusions">
          <title>Conclusions</title>
          <p>Health organizations should consider health literacy of the public when creating content to help prevent misinterpretation and perpetuate prevailing misperceptions surrounding DUIC. Delivering high quality, readable, and accurate information in a way that is comprehensible to the public is needed to support informed decision-making.</p>
        </sec>
      </abstract>
      <kwd-group>
        <kwd>cannabis</kwd>
        <kwd>driving</kwd>
        <kwd>quality</kwd>
        <kwd>readability</kwd>
        <kwd>accuracy</kwd>
        <kwd>public education</kwd>
        <kwd>internet</kwd>
        <kwd>Google search</kwd>
        <kwd>analysis</kwd>
        <kwd>accessibility</kwd>
        <kwd>information</kwd>
        <kwd>evaluation</kwd>
        <kwd>tool</kwd>
        <kwd>data</kwd>
        <kwd>misinterpretation</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec sec-type="introduction">
      <title>Introduction</title>
      <p>In October 2018, the use of nonmedical cannabis became legal in Canada [<xref ref-type="bibr" rid="ref1">1</xref>]. By the end of 2020, approximately 20% of Canadians, aged 15 years and older, reported using cannabis over the previous 3 months [<xref ref-type="bibr" rid="ref2">2</xref>]. Certain cannabis use behaviors can increase the risk of experiencing harmful effects [<xref ref-type="bibr" rid="ref3">3</xref>], such as daily use of cannabis, using cannabis products with high tetrahydrocannabinol content, or driving under the influence of cannabis (DUIC) [<xref ref-type="bibr" rid="ref4">4</xref>]. In Canada, approximately 1-2 out of every 5 cannabis consumers engage in some form of risky behaviors [<xref ref-type="bibr" rid="ref3">3</xref>], with 4%-12% of all injuries and deaths from motor vehicle accidents being attributed to DUIC [<xref ref-type="bibr" rid="ref5">5</xref>]. Additionally, 40% of participants in a Canada-wide survey reported riding with a cannabis-impaired driver within the past year [<xref ref-type="bibr" rid="ref6">6</xref>].</p>
      <p>There are mixed perceptions among the general public regarding the true risks associated with cannabis use [<xref ref-type="bibr" rid="ref7">7</xref>-<xref ref-type="bibr" rid="ref9">9</xref>]. In particular, the mixed beliefs regarding the risks associated with DUIC are concerning given the potential impact on both the consumer and innocent members of the public. Recent literature reported that perception of risks associated with DUIC is low, with one study reporting that 28% of participants believed there was no increased risk of accidents [<xref ref-type="bibr" rid="ref6">6</xref>]. Another study reported that of those who participated in DUIC, 43% believed it was not a risky behavior [<xref ref-type="bibr" rid="ref10">10</xref>]. This highlights the need to ensure cannabis consumers have access to evidence-based information to support informed decision-making [<xref ref-type="bibr" rid="ref7">7</xref>,<xref ref-type="bibr" rid="ref11">11</xref>,<xref ref-type="bibr" rid="ref12">12</xref>].</p>
      <p>Although information about cannabis can be retrieved from numerous sources, one study reported that 78% of participants relied on knowledge gained from their own personal experiences, while 39% obtained information from the internet [<xref ref-type="bibr" rid="ref13">13</xref>]. Cannabis-related Google searches increased by 75% between 2004 and 2016 [<xref ref-type="bibr" rid="ref14">14</xref>,<xref ref-type="bibr" rid="ref15">15</xref>]; however, the trustworthiness of information retrieved on the internet is questionable. There have been studies that explored the quality of cannabis labels from products sold on the web [<xref ref-type="bibr" rid="ref16">16</xref>], the accuracy of cannabis claims on common websites [<xref ref-type="bibr" rid="ref17">17</xref>], and the quality of cannabis-related information in magazines and newspapers [<xref ref-type="bibr" rid="ref18">18</xref>,<xref ref-type="bibr" rid="ref19">19</xref>]. In general, these studies reported that the quality of cannabis-related information were very poor. Among studies that specifically looked at cannabis health claims on the internet, one found only 5% of claims on the health benefits of cannabis aligned with evidence [<xref ref-type="bibr" rid="ref20">20</xref>]. Other studies reported that web-based information about cannabis use for pain was biased as sources often neglected to discuss potential risks [<xref ref-type="bibr" rid="ref21">21</xref>] or were just unreliable [<xref ref-type="bibr" rid="ref22">22</xref>]. This points to variable quality of cannabis-related information available on the internet [<xref ref-type="bibr" rid="ref20">20</xref>,<xref ref-type="bibr" rid="ref23">23</xref>-<xref ref-type="bibr" rid="ref26">26</xref>].</p>
      <p>Web-based search trends related to health-related topics provide insight on the public perception or cannabis use, which also reflect the availability of public health resources [<xref ref-type="bibr" rid="ref27">27</xref>]. Taking into consideration that searches related to cannabis increased by 75% on Google from 2004 to 2016 [<xref ref-type="bibr" rid="ref14">14</xref>,<xref ref-type="bibr" rid="ref15">15</xref>], high quality, easily accessible, evidence-based information is needed for individuals to make informed decisions about cannabis use behaviors [<xref ref-type="bibr" rid="ref28">28</xref>], which is especially important given the prevalent misconceptions about DUIC. However, the quality, readability, and accuracy of information found through the Google search engine on DUIC are still unknown [<xref ref-type="bibr" rid="ref6">6</xref>]. The purpose of this study was to assess the quality, readability, and accuracy of information about DUIC found on the internet through the Google search engine.</p>
    </sec>
    <sec sec-type="methods">
      <title>Methods</title>
      <sec>
        <title>Study Design</title>
        <p>A quantitative content analysis about DUIC was performed on public web pages using the Google Canada search engine.</p>
      </sec>
      <sec>
        <title>Eligibility Criteria</title>
        <p>To be included, the web page had to (1) have information related to cannabis and driving, (2) be available in English, (3) be accessible with no fee, (4) have text to analyze, and (5) be available at the time of analysis. Web pages were excluded if (1) the page became no longer available during analysis and (2) the web page only contained images.</p>
      </sec>
      <sec>
        <title>Data Collection</title>
        <p>Web pages were identified through the Google search engine. Google was chosen because it is the dominant search engine in Canada, holding 91.98% of market shares [<xref ref-type="bibr" rid="ref29">29</xref>], and one study showed that 89.8% of people preferred using Google [<xref ref-type="bibr" rid="ref30">30</xref>]. A private search through incognito mode was used to avoid the search history from biasing results. Six separate Google searches were performed using the terms outlined in <xref ref-type="boxed-text" rid="box1">Textbox 1</xref>, and the first 20 URLs were collected from each search. Neutral search terms were used to ensure the collected web pages were not biased in one direction. The first 20 URLs were collected, as most people consider no more than the first 20 web pages when performing an internet search [<xref ref-type="bibr" rid="ref15">15</xref>,<xref ref-type="bibr" rid="ref31">31</xref>]. For our study, one researcher (SS or MJ) extracted web page addresses with Google Chrome (version 99.0.4844.51) [<xref ref-type="bibr" rid="ref32">32</xref>]. The search was first completed in October 2021 using the first 4 search terms and then repeated fully in April 2022 after 2 new search terms were added.</p>
        <boxed-text id="box1" position="float">
          <title>Search terms used to collect web pages for analysis.</title>
          <p>
            <bold>Google search terms</bold>
          </p>
          <list list-type="bullet">
            <list-item>
              <p>Cannabis AND driving</p>
            </list-item>
            <list-item>
              <p>Marijuana AND driving</p>
            </list-item>
            <list-item>
              <p>Pot AND driving</p>
            </list-item>
            <list-item>
              <p>Weed AND driving</p>
            </list-item>
            <list-item>
              <p>Driving high</p>
            </list-item>
            <list-item>
              <p>Driving stoned</p>
            </list-item>
          </list>
        </boxed-text>
      </sec>
      <sec>
        <title>Data Analysis</title>
        <p>Web pages were organized into categories based on categories used in similar studies that assessed the quality of health-related information on the internet [<xref ref-type="bibr" rid="ref33">33</xref>]. These categories included digital media, commercial web pages, government organizations, health organizations, nonprofit foundations, peer-reviewed materials, and “other.”</p>
      </sec>
      <sec>
        <title>Outcome Measures</title>
        <sec>
          <title>Quality of Information</title>
          <p>The quality of the information was measured by 2 tools: the Health on the Net (HON) code and the Quality Evaluation Scoring Tool (QUEST).</p>
          <sec>
            <title>HON Code</title>
            <p>HON is a nonprofit foundation aimed to assess and evaluate the quality of web-based health information [<xref ref-type="bibr" rid="ref34">34</xref>]. The HON certification is designed so that people of the general public can identify trustworthy sources of information [<xref ref-type="bibr" rid="ref34">34</xref>] and has been used in previous research to evaluate health-related websites as a beneficial tool that shows the intent of a website to publish high-quality information [<xref ref-type="bibr" rid="ref35">35</xref>-<xref ref-type="bibr" rid="ref38">38</xref>].The HON code seeks to promote trustworthy health information for the benefit of internet users [<xref ref-type="bibr" rid="ref39">39</xref>]. HON code is a voluntary certification used on health websites, indicating that their 8 principles were fulfilled. Those principles relate to the authority, complementarity, confidentiality, attribution, justifiability, transparency, financial disclosure, and advertisement policy of the website content [<xref ref-type="bibr" rid="ref40">40</xref>]. This certification aims to certify websites that are reliable and of high quality, so it is an easy measure for the general public to quickly determine if the web page is a trustworthy source of health information.</p>
          </sec>
          <sec>
            <title>The QUEST Tool</title>
            <p>The QUEST tool serves as a standard for assessing the quality of web-based health information that does not rely on users’ subjective judgment [<xref ref-type="bibr" rid="ref41">41</xref>]. The QUEST tool was chosen as it has been validated and assessed for reliability and provides a numeric score allowing for quantitative analysis [<xref ref-type="bibr" rid="ref42">42</xref>]. The QUEST tool was validated for both treatment and preventative measures of web-based health care information [<xref ref-type="bibr" rid="ref41">41</xref>] and has since been used in studies to evaluate web-based health care information on various topics, including papillomavirus and oropharyngeal cancer, COVID-19, and using electronic cigarettes [<xref ref-type="bibr" rid="ref33">33</xref>,<xref ref-type="bibr" rid="ref43">43</xref>,<xref ref-type="bibr" rid="ref44">44</xref>]. Additionally, this tool is used for a broad range of health topics as opposed to more focused health topics (eg, treatment) [<xref ref-type="bibr" rid="ref41">41</xref>]. The QUEST tool assesses 7 aspects of the website information and provides a weighted score out of 28 (<xref ref-type="table" rid="table1">Table 1</xref>) [<xref ref-type="bibr" rid="ref41">41</xref>]. Three independent researchers collaborated to assess the quality of the web page, while each page was assessed by at least two researchers (SS, MJ, MB), and any discrepancies were discussed. For our study, if an organization took ownership over the text (rather than a specific author), we gave a score of 1, meaning “all other indications of authorship” on the QUEST tool scoring. Additionally, any language that promoted the sale of cannabis (eg, cannabis brand) or directed the reader to a specific location for purchase was given a score of 1 accordingly under the “Conflicts of Interest” section of the QUEST scoring tool. For example, any mention of a specific cannabis dispensary, even if indirectly mentioned through a picture identifying a dispensary, was considered an endorsement, and therefore, had the potential to be biased.</p>
            <table-wrap position="float" id="table1">
              <label>Table 1</label>
              <caption>
                <p>Description of the Quality Evaluation Scoring Tool (QUEST) criteria to evaluate the quality of web-based health information [<xref ref-type="bibr" rid="ref41">41</xref>]. Scores in the individual sections are weighted and summed to generate a total score of up to 28. This tool is reproduced and distributed under the terms of the Creative Commons Attribution 4.0 International License [<xref ref-type="bibr" rid="ref45">45</xref>].</p>
              </caption>
              <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
                <col width="30"/>
                <col width="0"/>
                <col width="30"/>
                <col width="830"/>
                <col width="0"/>
                <col width="0"/>
                <col width="110"/>
                <thead>
                  <tr valign="top">
                    <td colspan="6">Characteristics</td>
                    <td>Score</td>
                  </tr>
                </thead>
                <tbody>
                  <tr valign="top">
                    <td colspan="6">
                      <bold>Authorship</bold>
                    </td>
                    <td>Score x 1</td>
                  </tr>
                  <tr valign="top">
                    <td>
                      <break/>
                    </td>
                    <td colspan="5">0: No indication of authorship or username</td>
                    <td>
                      <break/>
                    </td>
                  </tr>
                  <tr valign="top">
                    <td>
                      <break/>
                    </td>
                    <td colspan="5">1: All other indications of authorship</td>
                    <td>
                      <break/>
                    </td>
                  </tr>
                  <tr valign="top">
                    <td>
                      <break/>
                    </td>
                    <td colspan="5">2: Author’s name and qualification clearly stated</td>
                    <td>
                      <break/>
                    </td>
                  </tr>
                  <tr valign="top">
                    <td colspan="6">
                      <bold>Attribution</bold>
                    </td>
                    <td>Score x 3</td>
                  </tr>
                  <tr valign="top">
                    <td>
                      <break/>
                    </td>
                    <td colspan="5">0: No sources</td>
                    <td>
                      <break/>
                    </td>
                  </tr>
                  <tr valign="top">
                    <td>
                      <break/>
                    </td>
                    <td colspan="5">1: Mention of expert source, research, research findings (although with insufficient information to identify the specific studies), links to various sites, advocacy body, or other</td>
                    <td>
                      <break/>
                    </td>
                  </tr>
                  <tr valign="top">
                    <td>
                      <break/>
                    </td>
                    <td colspan="5">2: Reference to at least one identifiable scientific study, regardless of format (eg, information in text or reference list)</td>
                    <td>
                      <break/>
                    </td>
                  </tr>
                  <tr valign="top">
                    <td>
                      <break/>
                    </td>
                    <td colspan="5">3: Reference to mainly identifiable scientific studies, regardless of format (in &gt;50% of claims)</td>
                    <td>
                      <break/>
                    </td>
                  </tr>
                  <tr valign="top">
                    <td>
                      <break/>
                    </td>
                    <td>
                      <break/>
                    </td>
                    <td colspan="3">
                      <bold>Type of study (for all articles scoring 2 or 3 on “attribution”)</bold>
                    </td>
                    <td colspan="2">Score x 1</td>
                  </tr>
                  <tr valign="top">
                    <td>
                      <break/>
                    </td>
                    <td>
                      <break/>
                    </td>
                    <td>
                      <break/>
                    </td>
                    <td>0: In vitro, animal models, and editorials</td>
                    <td colspan="3">
                      <break/>
                    </td>
                  </tr>
                  <tr valign="top">
                    <td>
                      <break/>
                    </td>
                    <td>
                      <break/>
                    </td>
                    <td>
                      <break/>
                    </td>
                    <td>1: All observational works</td>
                    <td colspan="3">
                      <break/>
                    </td>
                  </tr>
                  <tr valign="top">
                    <td>
                      <break/>
                    </td>
                    <td>
                      <break/>
                    </td>
                    <td>
                      <break/>
                    </td>
                    <td>2: Meta-analyses, randomized controlled trials, and clinical studies</td>
                    <td colspan="3">
                      <break/>
                    </td>
                  </tr>
                  <tr valign="top">
                    <td colspan="6">
                      <bold>Conflicts of interest</bold>
                    </td>
                    <td>Score x 3</td>
                  </tr>
                  <tr valign="top">
                    <td>
                      <break/>
                    </td>
                    <td colspan="5">0: Endorsement or promotion of intervention designed to prevent or treat condition (eg, supplements, brain training games, and foods) within the article</td>
                    <td>
                      <break/>
                    </td>
                  </tr>
                  <tr valign="top">
                    <td>
                      <break/>
                    </td>
                    <td colspan="5">1: Endorsement or promotion of educational products and services (eg, book and care home services)</td>
                    <td>
                      <break/>
                    </td>
                  </tr>
                  <tr valign="top">
                    <td>
                      <break/>
                    </td>
                    <td colspan="5">2: Unbiased information</td>
                    <td>
                      <break/>
                    </td>
                  </tr>
                  <tr valign="top">
                    <td colspan="6">
                      <bold>Currency</bold>
                    </td>
                    <td>Score x 1</td>
                  </tr>
                  <tr valign="top">
                    <td>
                      <break/>
                    </td>
                    <td colspan="5">0: No date present</td>
                    <td>
                      <break/>
                    </td>
                  </tr>
                  <tr valign="top">
                    <td>
                      <break/>
                    </td>
                    <td colspan="5">1: Article is dated but is 5 years or older</td>
                    <td>
                      <break/>
                    </td>
                  </tr>
                  <tr valign="top">
                    <td>
                      <break/>
                    </td>
                    <td colspan="5">2: Article is dated within the last 5 years</td>
                    <td>
                      <break/>
                    </td>
                  </tr>
                  <tr valign="top">
                    <td colspan="6">
                      <bold>Complimentary</bold>
                    </td>
                    <td>Score x 1</td>
                  </tr>
                  <tr valign="top">
                    <td>
                      <break/>
                    </td>
                    <td colspan="5">0: No support of the patient-physician relationship</td>
                    <td>
                      <break/>
                    </td>
                  </tr>
                  <tr valign="top">
                    <td>
                      <break/>
                    </td>
                    <td colspan="5">1: Support of the patient-physician relationship</td>
                    <td>
                      <break/>
                    </td>
                  </tr>
                  <tr valign="top">
                    <td colspan="6">
                      <bold>Tone (includes title)</bold>
                    </td>
                    <td>Score x 3</td>
                  </tr>
                  <tr valign="top">
                    <td>
                      <break/>
                    </td>
                    <td colspan="5">0: Fully supported—authors fully and unequivocally support the claims; strong vocabulary is used, such as “cure,” “guarantee,” and “easy”; use of nonconditional verb tenses mostly (eg, “can” and “will”); and no discussion of limitations</td>
                    <td>
                      <break/>
                    </td>
                  </tr>
                  <tr valign="top">
                    <td>
                      <break/>
                    </td>
                    <td colspan="5">1: Mainly supported (authors mainly support their claims but with more cautious vocabulary, such as “can reduce your risk” or “may help prevent”, and no discussion of limitations)</td>
                    <td>
                      <break/>
                    </td>
                  </tr>
                  <tr valign="top">
                    <td>
                      <break/>
                    </td>
                    <td colspan="5">2: Balanced or cautious support (authors’ claims are balanced by caution and include statements of limitations and contrasting findings)</td>
                    <td>
                      <break/>
                    </td>
                  </tr>
                </tbody>
              </table>
            </table-wrap>
          </sec>
        </sec>
        <sec>
          <title>Readability</title>
          <p>Web page content was assessed for readability by the general public using 4 different scales, including Gunning Fox Index (GFI), Flesch Reading Ease Scale (FRES), Flesh-Kincaid Grade Level (FKGL), and the Simple Measure of Gobbledygook (SMOG) scale (<xref ref-type="table" rid="table2">Table 2</xref>). There are many scales to measure the readability of information [<xref ref-type="bibr" rid="ref46">46</xref>], but there is no universally accepted measurement of readability. Therefore, the combination of these 4 readability scores (ie, GFI, FRES, FKGL, and SMOG) has been used together to measure the readability of health information [<xref ref-type="bibr" rid="ref33">33</xref>,<xref ref-type="bibr" rid="ref47">47</xref>] in this study. Each web page URL was submitted to the Readable [<xref ref-type="bibr" rid="ref48">48</xref>] web-based scoring tool by one researcher (DG). If the URL was directed to a PDF, the text was manually entered into the web-based generator by copying and pasting the titles and content. Text were excluded from the analysis if they were advertisements, hyperlinks, author names, or references, as these could bias the results [<xref ref-type="bibr" rid="ref47">47</xref>]. The scores were compared to a value unique to each readability tool that indicated the content was universally readable.</p>
          <table-wrap position="float" id="table2">
            <label>Table 2</label>
            <caption>
              <p>Tools used to measure readability, their range of scores, the score correlated to text that is readable by the general public, and the formula used to calculate the score.</p>
            </caption>
            <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
              <col width="160"/>
              <col width="120"/>
              <col width="260"/>
              <col width="460"/>
              <thead>
                <tr valign="top">
                  <td>Readability tool</td>
                  <td>Range</td>
                  <td>Readable by the general public</td>
                  <td>Formula</td>
                </tr>
              </thead>
              <tbody>
                <tr valign="top">
                  <td>GFI<sup>a</sup></td>
                  <td>0-20</td>
                  <td>&lt;8 [<xref ref-type="bibr" rid="ref49">49</xref>]</td>
                  <td>
                    <inline-graphic xlink:href="infodemiology_v3i1e43001_fig3.png" xlink:type="simple" mimetype="image"/>
                  </td>
                </tr>
                <tr valign="top">
                  <td>FRES<sup>b</sup></td>
                  <td>0-100</td>
                  <td>&gt;60 [<xref ref-type="bibr" rid="ref47">47</xref>]</td>
                  <td>
                    <inline-graphic xlink:href="infodemiology_v3i1e43001_fig4.png" xlink:type="simple" mimetype="image"/>
                  </td>
                </tr>
                <tr valign="top">
                  <td>FKGL<sup>c</sup></td>
                  <td>0-18</td>
                  <td>&lt;8 [<xref ref-type="bibr" rid="ref47">47</xref>,<xref ref-type="bibr" rid="ref50">50</xref>]</td>
                  <td>
                    <inline-graphic xlink:href="infodemiology_v3i1e43001_fig5.png" xlink:type="simple" mimetype="image"/>
                  </td>
                </tr>
                <tr valign="top">
                  <td>SMOG<sup>d</sup></td>
                  <td>—<sup>e</sup></td>
                  <td>&lt;10 [<xref ref-type="bibr" rid="ref47">47</xref>]</td>
                  <td>
                    <inline-graphic xlink:href="infodemiology_v3i1e43001_fig6.png" xlink:type="simple" mimetype="image"/>
                  </td>
                </tr>
              </tbody>
            </table>
            <table-wrap-foot>
              <fn id="table2fn1">
                <p><sup>a</sup>GFI: Gunning Fox Index.</p>
              </fn>
              <fn id="table2fn2">
                <p><sup>b</sup>FRES: Flesch Reading Ease Scale.</p>
              </fn>
              <fn id="table2fn3">
                <p><sup>c</sup>FKGL: Flesch-Kincaid Grade Level.</p>
              </fn>
              <fn id="table2fn4">
                <p><sup>d</sup>SMOG: Simple Measure of Gobbledygook.</p>
              </fn>
              <fn id="table2fn5">
                <p><sup>e</sup>Not applicable.</p>
              </fn>
            </table-wrap-foot>
          </table-wrap>
        </sec>
        <sec>
          <title>Accuracy</title>
          <p>The 5Cs Website Evaluation Tool is a structured tool that evaluates websites using 36 questions, grouped into the following 5 accuracy criteria: credibility, currency, content, construction, and clarity [<xref ref-type="bibr" rid="ref51">51</xref>]. Since the construction, credibility, currency, and content of websites included in this study were assessed with the quality and readability tools, we only applied the content criteria.</p>
          <p>The tool asks if the information on the website is evidence based and represents information from published journals and books [<xref ref-type="bibr" rid="ref51">51</xref>]. To complete this assessment, current evidence from peer-reviewed journals was gathered, as they pertain to 5 key topics related to cannabis and driving (<xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref>). These topics include (1) the effects of cannabis consumption, (2) the prevalence of DUIC, (3) the effects of cannabis on driving performance, (4) risk of collision after using cannabis, and (5) the detection of cannabis-impaired drivers by law enforcement.</p>
          <p>Each web page was assessed for the content across the 5 key categories. For each topic, the web page content was rated as accurate, not accurate, mixed accuracy (ie, some statements were accurate and some were not, or information was not aligning with the literature), or information not present. Each web page was rated independently by 2 researchers (MJ and DG); discrepancies were discussed and resolved. Web pages categorized as peer-reviewed (ie, peer-reviewed journal articles) were not included in the accuracy analysis, as peer-reviewed literature was used to create the evidence-based summary used in the content assessment. This approach has been used by others conducting similar content analyses [<xref ref-type="bibr" rid="ref21">21</xref>].</p>
        </sec>
      </sec>
      <sec>
        <title>Statistical Analysis</title>
        <p>Descriptive statistics was performed with the mean (μ), standard deviation (σ), and total sample size (n) being reported for the average QUEST score of all web pages and by category. To assess correlations between QUEST scores and readability scores (ie, GFI, FRES, FKGL, and SMOG), a Pearson 2-tailed test was performed [<xref ref-type="bibr" rid="ref33">33</xref>]. To assess the QUEST score for the presence of the HON code, an unpaired 1-tailed <italic>t</italic> test was performed, testing if the HON code was present on web pages with higher QUEST scores [<xref ref-type="bibr" rid="ref33">33</xref>].</p>
      </sec>
      <sec>
        <title>Ethics Approval</title>
        <p>This study was exempted from ethical approval because it does not involve human participants.</p>
      </sec>
    </sec>
    <sec sec-type="results">
      <title>Results</title>
      <sec>
        <title>Overview</title>
        <p>A total of 120 web pages were identified for analysis (<xref ref-type="supplementary-material" rid="app2">Multimedia Appendix 2</xref>). Of the 120 web pages, 34 were removed as duplicate web pages, and 4 were removed as they did not meet the eligibility criteria, leaving 82 web pages included in the study (<xref rid="figure1" ref-type="fig">Figure 1</xref>). Of these, 40% (33/82) of web pages were categorized as digital media, 20% (16/82) as commercial web pages, 13% (11/82) as government organizations, 12% (10/82) as health organizations, 10% (8/82) as nonprofit foundations, 4% (3/82) as peer-reviewed content, and 1% (1/82) as “other.” <xref ref-type="supplementary-material" rid="app3">Multimedia Appendix 3</xref> presents the web pages included in the data analysis.</p>
        <fig id="figure1" position="float">
          <label>Figure 1</label>
          <caption>
            <p>Included and excluded web pages for quantitative analysis of quality, readability, and accuracy. QUEST: quality evaluation scoring tool.</p>
          </caption>
          <graphic xlink:href="infodemiology_v3i1e43001_fig1.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
        </fig>
      </sec>
      <sec>
        <title>Quality</title>
        <p>The range of the QUEST scores was between 7 and 27, with the average Quest score being 17.4 (SD 5.6) out of a total of 28 (<xref ref-type="table" rid="table3">Table 3</xref>). Average QUEST scores by category showed that the peer-reviewed category had the highest quality with a score of 26.3 out of 28, and government web pages scored the lowest at 10.0/28.</p>
        <p>The HON code was only present on 4 (5%) web pages, and they were found in the categories labelled as commercial (n=2), nonprofit (n=1), or health organization (n=1). There was no significant difference (<italic>P</italic>=.2) between the presence of a HON code on a website and the QUEST score without a HON code. <xref ref-type="supplementary-material" rid="app4">Multimedia Appendix 4</xref> presents the data from the full quality evaluation for each web page.</p>
        <table-wrap position="float" id="table3">
          <label>Table 3</label>
          <caption>
            <p>Quality Evaluation Scoring Tool (QUEST) scores by category.</p>
          </caption>
          <table border="1" rules="groups" cellpadding="5" frame="hsides" width="1000" cellspacing="0">
            <col width="300"/>
            <col width="200"/>
            <col width="200"/>
            <col width="300"/>
            <thead>
              <tr valign="top">
                <td>Category</td>
                <td colspan="3">QUEST score</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Mean (μ)</td>
                <td>SD (σ)</td>
                <td>Total, n</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td>Peer-reviewed content</td>
                <td>26.3</td>
                <td>0.6</td>
                <td>3</td>
              </tr>
              <tr valign="top">
                <td>Health organizations</td>
                <td>20.5</td>
                <td>5.6</td>
                <td>10</td>
              </tr>
              <tr valign="top">
                <td>Other</td>
                <td>N/A<sup>a</sup></td>
                <td>N/A</td>
                <td>1</td>
              </tr>
              <tr valign="top">
                <td>Digital media</td>
                <td>19.5</td>
                <td>3.5</td>
                <td>33</td>
              </tr>
              <tr valign="top">
                <td>Commercial</td>
                <td>15.7</td>
                <td>6.0</td>
                <td>16</td>
              </tr>
              <tr valign="top">
                <td>Nonprofit foundations</td>
                <td>14.9</td>
                <td>4.2</td>
                <td>8</td>
              </tr>
              <tr valign="top">
                <td>Government</td>
                <td>10.0</td>
                <td>2.5</td>
                <td>11</td>
              </tr>
              <tr valign="top">
                <td>Total</td>
                <td>18.1</td>
                <td>5.6</td>
                <td>82</td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table3fn1">
              <p><sup>a</sup>N/A: not applicable.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
      </sec>
      <sec>
        <title>Readability</title>
        <p>The average readability scores were 9.7 (SD 2.3) for FKGL, 11.4 (SD 2.8) for GFI, 12.2 (SD 1.9) for SMOG index, and 49.9 (SD 12.3) for FRES. Assessing the readability scores for all web pages in relation to the universal readability score, 19.5% (16/82) of the web pages were universally readable by the FKGL score (score &lt;8 considered universally readable), 16% (13/82) by the FRES score (score &gt;60 considered universally readable), 11.1% (9/82) by the SMOG index (score &lt;10 considered universally readable), and 9.8% (8/82) by the GFI score (score &lt;8 considered universally readable). None of the web pages in the peer-reviewed or other categories were considered universally readable by any readability scoring tool (<xref ref-type="table" rid="table4">Table 4</xref>). <xref ref-type="supplementary-material" rid="app5">Multimedia Appendix 5</xref> presents the readability scores for each web page.</p>
        <table-wrap position="float" id="table4">
          <label>Table 4</label>
          <caption>
            <p>Web pages by category that were considered universally readable.</p>
          </caption>
          <table border="1" rules="groups" cellpadding="5" frame="hsides" width="1000" cellspacing="0">
            <col width="300"/>
            <col width="160"/>
            <col width="160"/>
            <col width="160"/>
            <col width="220"/>
            <thead>
              <tr valign="top">
                <td>Category</td>
                <td colspan="4">Web pages, n (%)</td>
              </tr>
              <tr valign="top">
                <td/>
                <td>FKGL<sup>a</sup></td>
                <td>GFI<sup>b</sup></td>
                <td>SMOG<sup>c</sup></td>
                <td>FRES<sup>d</sup></td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td>Commercial (n=16)</td>
                <td>3 (19)</td>
                <td>2 (13)</td>
                <td>1 (6)</td>
                <td>4 (25)</td>
              </tr>
              <tr valign="top">
                <td>Digital media (n=33)</td>
                <td>4 (12)</td>
                <td>2 (6)</td>
                <td>3 (9)</td>
                <td>3 (9)</td>
              </tr>
              <tr valign="top">
                <td>Government (n=11)</td>
                <td>4 (36)</td>
                <td>3 (27)</td>
                <td>3 (27)</td>
                <td>4 (36)</td>
              </tr>
              <tr valign="top">
                <td>Other (n=1)</td>
                <td>0 (0)</td>
                <td>0 (0)</td>
                <td>0 (0)</td>
                <td>0 (0)</td>
              </tr>
              <tr valign="top">
                <td>Nonprofit foundations (n=8)</td>
                <td>2 (25)</td>
                <td>0 (0)</td>
                <td>1 (13)</td>
                <td>1 (13)</td>
              </tr>
              <tr valign="top">
                <td>Peer-reviewed material (n=3)</td>
                <td>0 (0)</td>
                <td>0 (0)</td>
                <td>0 (0)</td>
                <td>0 (0)</td>
              </tr>
              <tr valign="top">
                <td>Health organization (n=10)</td>
                <td>3 (30)</td>
                <td>1 (10)</td>
                <td>1 (10)</td>
                <td>1 (10)</td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table4fn1">
              <p><sup>a</sup>FKGL: Flesh-Kincaid Grade Level.</p>
            </fn>
            <fn id="table4fn2">
              <p><sup>b</sup>GFI: Gunning Fox Index.</p>
            </fn>
            <fn id="table4fn3">
              <p><sup>c</sup>SMOG: Simple Measure of Gobbledygook.</p>
            </fn>
            <fn id="table4fn4">
              <p><sup>d</sup>FRES: Flesch Reading Ease Scale.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
      </sec>
      <sec>
        <title>Correlation Between Quality and Readability</title>
        <p>A Pearson 2-tailed test showed a significant positive correlation between the QUEST score and the FKGL (<italic>r</italic>=0.41; <italic>P</italic>&lt;.001), GFI (<italic>r</italic>=0.28; <italic>P</italic>=.01), and SMOG (<italic>r</italic>=0.34; <italic>P</italic>=.002) readability scores. A negative correlation was found between the QUEST score and the FRES score (<italic>r</italic>=–0.40; <italic>P</italic>&lt;.001).</p>
      </sec>
      <sec>
        <title>Accuracy</title>
        <p>Of the 79 web pages that were eligible to be reviewed for accuracy, 23 web pages discussed information related to the timing of the effects from cannabis consumption; 31 web pages were related to the prevalence of DUIC; 53 were related to the effects of cannabis impairment on driving ability; 51 were related to the risk of collision; and 49 had information related to detection by law (<xref rid="figure2" ref-type="fig">Figure 2</xref>). From those, 96% (22/23) had accurate information on the effects from cannabis consumption; 97% (30/31) of the web pages had accurate information about the prevalence of DUIC; 92% (49/53) of the web pages presented accurate information on the effects of cannabis impairment on driving ability; 80% (41/51) of the web pages had accurate information on the risk of collision; and 71% (35/49) of the web pages presented accurate information on detection by law. Sample excerpts from web pages and accuracy categorization are included in <xref ref-type="supplementary-material" rid="app6">Multimedia Appendix 6</xref>.</p>
        <fig id="figure2" position="float">
          <label>Figure 2</label>
          <caption>
            <p>Accuracy ratings of web page content. Content accuracy of the 5 key topics about driving under the influence of cannabis are represented with colors.</p>
          </caption>
          <graphic xlink:href="infodemiology_v3i1e43001_fig2.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
        </fig>
      </sec>
    </sec>
    <sec sec-type="discussion">
      <title>Discussion</title>
      <sec>
        <title>Principal Findings</title>
        <p>This study assessed the quality, readability, and accuracy of information about DUIC found on the internet using the Google search engine. Our findings showed that peer-reviewed papers had the highest quality of information; however, these web pages were not considered universally readable. The difficulty with comprehension may lead to misinterpretation and inaccurate expectations [<xref ref-type="bibr" rid="ref52">52</xref>,<xref ref-type="bibr" rid="ref53">53</xref>].</p>
        <p>Surprisingly, our research indicated that government web pages were rated as having the lowest quality, contrary to the general perception that government sources would contain high-quality information. This low rating was likely attributed to the tone of the presented text, given much of the information on government websites was one-sided, used strong words such as “will,” and did not discuss limitations of the information presented. This low quality could be due to the fact that government websites often presented information on laws and regulations and did not provide references to other information. This is unfortunate, as government web pages are typically viewed as an accurate source of information as indicated by various academic guides for evaluating information sources [<xref ref-type="bibr" rid="ref54">54</xref>,<xref ref-type="bibr" rid="ref55">55</xref>].</p>
        <p>Readability for the public was problematic for most pages, with less than 20% of all web pages considered readable based on the FKGL, GFI, SMOG, and FRES readability tools. The majority of the content was written at a higher level of reading, which would often be used in academic settings or postsecondary education. The paucity of web pages written at levels that were considered universally readable was consistent with other health information topics on the internet (eg, general surgical procedures [<xref ref-type="bibr" rid="ref56">56</xref>] and total joint arthroplasty [<xref ref-type="bibr" rid="ref57">57</xref>]), suggesting that this could be a wider issue than solely information on cannabis [<xref ref-type="bibr" rid="ref33">33</xref>,<xref ref-type="bibr" rid="ref47">47</xref>,<xref ref-type="bibr" rid="ref58">58</xref>]. Kruger et al [<xref ref-type="bibr" rid="ref58">58</xref>] also suggests that significant efforts are still needed to provide accurate cannabis-related information on the internet for the health and safety of individuals and society [<xref ref-type="bibr" rid="ref58">58</xref>].</p>
        <p>The readability could be contributing to the misperceptions and behaviors; however, further studies assessing the interpretation of high-quality information with low readability scores could be beneficial. Associations and health advocacy groups should consider the health literacy of the public [<xref ref-type="bibr" rid="ref59">59</xref>] when creating content to educate the public on DUIC. In addition, a more active form of education for the public could be beneficial as opposed to the passive information presented on a web page.</p>
        <p>Our research shows that 80% of the information available about DUIC and its risks for accidents was accurate. However, although most information on DUIC was accurate, it was the lack of complete information that was most concerning. Of the 79 web pages that were analyzed for information about DUIC, 48% (n=38) either had no information on the risk of collision or had mixed or inaccurate information. Misperceptions surrounding cannabis particularly do not recognize the increased risk of accidents associated with DUIC, which highlights the need for comprehensive and accurate information [<xref ref-type="bibr" rid="ref6">6</xref>,<xref ref-type="bibr" rid="ref10">10</xref>], as many people turn to the internet to find information about cannabis [<xref ref-type="bibr" rid="ref8">8</xref>,<xref ref-type="bibr" rid="ref60">60</xref>] and about health in general [<xref ref-type="bibr" rid="ref61">61</xref>].</p>
        <p>Contrary to our finding that many web pages generally presented accurate information regarding DUIC, Lau et al [<xref ref-type="bibr" rid="ref20">20</xref>] found that around 80% of the internet claims were inaccurate when investigating the information related to cannabis health benefits. This may suggest that the evidence regarding DUIC is less debated compared to suggested health benefits of cannabis; still, DUIC behaviors persist despite the presence of easily accessible accurate information [<xref ref-type="bibr" rid="ref5">5</xref>,<xref ref-type="bibr" rid="ref6">6</xref>]. Studies have shown that both adolescents and adults have a low risk perception of cannabis [<xref ref-type="bibr" rid="ref62">62</xref>] and feel they are in control of their driving after cannabis consumption [<xref ref-type="bibr" rid="ref63">63</xref>]. This is problematic given the evidence that cannabis can significantly impair motor coordination, judgment, and reaction time [<xref ref-type="bibr" rid="ref64">64</xref>,<xref ref-type="bibr" rid="ref65">65</xref>], increasing the risk of motor vehicle accidents [<xref ref-type="bibr" rid="ref66">66</xref>].</p>
      </sec>
      <sec>
        <title>Limitations</title>
        <p>This study has a number of limitations. Although we have used what appears to be the most appropriate tools to evaluate web page information, there are no best practices for conducting this type of research. Second, the QUEST tool does not have a target quality score or a threshold of acceptable quality, and therefore, we can only make relative comparisons with the web pages included in this study. Finally, we made the assumption that peer-reviewed content was accurate and excluded those sites from the accuracy assessment. However, there is no guarantee that all peer-reviewed materials are fully accurate. Fortunately, only 3 web pages fell into this category, so this would have minimal impact on the overall analysis.</p>
      </sec>
      <sec>
        <title>Conclusions</title>
        <p>Most of the identified web pages on Google Canada search engine provided accurate information about DUIC; however, the information was incomplete, the readability was generally low, and the quality of information varied depending on the source. Health organizations should consider health literacy of the public when creating content to help prevent misinterpretation and perpetuate prevailing misperceptions surrounding DUIC. Delivering high-quality, readable, and accurate information in a way that is comprehensible to the public is needed to support informed decision-making.</p>
      </sec>
    </sec>
  </body>
  <back>
    <app-group>
      <supplementary-material id="app1">
        <label>Multimedia Appendix 1</label>
        <p>Supplementary material.</p>
        <media xlink:href="infodemiology_v3i1e43001_app1.pdf" xlink:title="PDF File  (Adobe PDF File), 158 KB"/>
      </supplementary-material>
      <supplementary-material id="app2">
        <label>Multimedia Appendix 2</label>
        <p>Web pages collected form each Google page.</p>
        <media xlink:href="infodemiology_v3i1e43001_app2.pdf" xlink:title="PDF File  (Adobe PDF File), 152 KB"/>
      </supplementary-material>
      <supplementary-material id="app3">
        <label>Multimedia Appendix 3</label>
        <p>Web pages included in the data analysis.</p>
        <media xlink:href="infodemiology_v3i1e43001_app3.pdf" xlink:title="PDF File  (Adobe PDF File), 137 KB"/>
      </supplementary-material>
      <supplementary-material id="app4">
        <label>Multimedia Appendix 4</label>
        <p>The quality assessment of the included web pages.</p>
        <media xlink:href="infodemiology_v3i1e43001_app4.pdf" xlink:title="PDF File  (Adobe PDF File), 264 KB"/>
      </supplementary-material>
      <supplementary-material id="app5">
        <label>Multimedia Appendix 5</label>
        <p>The readability scores of the included web pages.</p>
        <media xlink:href="infodemiology_v3i1e43001_app5.pdf" xlink:title="PDF File  (Adobe PDF File), 104 KB"/>
      </supplementary-material>
      <supplementary-material id="app6">
        <label>Multimedia Appendix 6</label>
        <p>Examples of quotations used for the accuracy assessment.</p>
        <media xlink:href="infodemiology_v3i1e43001_app6.pdf" xlink:title="PDF File  (Adobe PDF File), 95 KB"/>
      </supplementary-material>
    </app-group>
    <glossary>
      <title>Abbreviations</title>
      <def-list>
        <def-item>
          <term id="abb1">DUIC</term>
          <def>
            <p>driving under the influence of cannabis</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb2">FKGL</term>
          <def>
            <p>Flesch-Kincaid Grade Level</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb3">FRES</term>
          <def>
            <p>Flesch Reading Ease Scale</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb4">GFI</term>
          <def>
            <p>Gunning Fox Index</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb5">HON</term>
          <def>
            <p>Health on the Net</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb6">QUEST</term>
          <def>
            <p>quality evaluation scoring tool</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb7">SMOG</term>
          <def>
            <p>Simple Measure of Gobbledygook</p>
          </def>
        </def-item>
      </def-list>
    </glossary>
    <ack>
      <p>Sandra Schuhmacher, BSc, PharmD Student, has applied the search strategy and extracted the Health on the Net (HON) code for each web page. The authors received financial support for conduct of the research from Canadian Institutes of Health Research (Grant No. RN407334 - 429120) and the Canadian Centre of Substance Use and Addiction for the Partnerships for Cannabis Policy (Grant No. RN407334 - 429120) inclusive of this research.</p>
    </ack>
    <fn-group>
      <fn fn-type="con">
        <p>All authors have contributed to the design of this study. MJ carried out the search strategy; MJ and MB applied the QUEST tool. DG rated the readability for the web pages. MJ and DG assessed the accuracy of the web pages. All authors contributed to the analysis of the findings. MJ wrote the initial manuscript, and DG helped to draft the manuscript. JD, LDB, and MN conceptualized the research, reviewed discrepancies, developed the accuracy tool, and reviewed the manuscript. All authors read and approved the final manuscript.</p>
      </fn>
      <fn fn-type="conflict">
        <p>None declared.</p>
      </fn>
    </fn-group>
    <ref-list>
      <ref id="ref1">
        <label>1</label>
        <nlm-citation citation-type="web">
          <article-title>Taking stock of progress: cannabis legalization and regulation in Canada</article-title>
          <source>Government of Canada</source>
          <year>2022</year>
          <access-date>2023-02-03</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.canada.ca/en/health-canada/programs/engaging-cannabis-legalization-regulation-canada-taking-stock-progress/document.html">https://tinyurl.com/bdfnn6kv</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref2">
        <label>2</label>
        <nlm-citation citation-type="web">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Rotermann</surname>
              <given-names>M</given-names>
            </name>
          </person-group>
          <article-title>Health report - Looking back from 2020, how cannabis use and related behaviours changed in Canada</article-title>
          <source>Statistics Canada</source>
          <year>2021</year>
          <month>04</month>
          <day>21</day>
          <access-date>2021-07-30</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www150.statcan.gc.ca/n1/pub/82-003-x/2021004/article/00001-eng.htm">https://www150.statcan.gc.ca/n1/pub/82-003-x/2021004/article/00001-eng.htm</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref3">
        <label>3</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Lee</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Lee</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Goodman</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Hammond</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Fischer</surname>
              <given-names>B</given-names>
            </name>
          </person-group>
          <article-title>The Lower-Risk Cannabis Use Guidelines' (LRCUG) recommendations: how are Canadian cannabis users complying?</article-title>
          <source>Prev Med Rep</source>
          <year>2020</year>
          <month>12</month>
          <volume>20</volume>
          <fpage>101187</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://linkinghub.elsevier.com/retrieve/pii/S2211-3355(20)30146-7"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.pmedr.2020.101187</pub-id>
          <pub-id pub-id-type="medline">33083205</pub-id>
          <pub-id pub-id-type="pii">S2211-3355(20)30146-7</pub-id>
          <pub-id pub-id-type="pmcid">PMC7554648</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref4">
        <label>4</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Fischer</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Russell</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Sabioni</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>van den Brink</surname>
              <given-names>W</given-names>
            </name>
            <name name-style="western">
              <surname>Le Foll</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Hall</surname>
              <given-names>W</given-names>
            </name>
            <name name-style="western">
              <surname>Rehm</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Room</surname>
              <given-names>R</given-names>
            </name>
          </person-group>
          <article-title>Lower-risk cannabis use guidelines: a comprehensive update of evidence and recommendations</article-title>
          <source>Am J Public Health</source>
          <year>2017</year>
          <month>08</month>
          <volume>107</volume>
          <issue>8</issue>
          <fpage>e1</fpage>
          <lpage>e12</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://ajph.aphapublications.org/doi/full/10.2105/AJPH.2017.303818"/>
          </comment>
          <pub-id pub-id-type="doi">10.2105/AJPH.2017.303818</pub-id>
          <pub-id pub-id-type="medline">28644037</pub-id>
          <pub-id pub-id-type="pmcid">PMC5508136</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref5">
        <label>5</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Fischer</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Imtiaz</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Rudzinski</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Rehm</surname>
              <given-names>J</given-names>
            </name>
          </person-group>
          <article-title>Crude estimates of cannabis-attributable mortality and morbidity in Canada-implications for public health focused intervention priorities</article-title>
          <source>J Public Health (Oxf)</source>
          <year>2016</year>
          <month>03</month>
          <day>28</day>
          <volume>38</volume>
          <issue>1</issue>
          <fpage>183</fpage>
          <lpage>8</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://europepmc.org/abstract/MED/25630540"/>
          </comment>
          <pub-id pub-id-type="doi">10.1093/pubmed/fdv005</pub-id>
          <pub-id pub-id-type="medline">25630540</pub-id>
          <pub-id pub-id-type="pii">fdv005</pub-id>
          <pub-id pub-id-type="pmcid">PMC4750519</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref6">
        <label>6</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Erin Goodman</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Leos-Toro</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Hammond</surname>
              <given-names>D</given-names>
            </name>
          </person-group>
          <article-title>Risk perceptions of cannabis- vs. alcohol-impaired driving among Canadian young people</article-title>
          <source>Drugs (Abingdon Engl)</source>
          <year>2019</year>
          <month>05</month>
          <day>16</day>
          <volume>27</volume>
          <issue>3</issue>
          <fpage>205</fpage>
          <lpage>212</lpage>
          <pub-id pub-id-type="doi">10.1080/09687637.2019.1611738</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref7">
        <label>7</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Turna</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Balodis</surname>
              <given-names>I</given-names>
            </name>
            <name name-style="western">
              <surname>Van Ameringen</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Busse</surname>
              <given-names>JW</given-names>
            </name>
            <name name-style="western">
              <surname>MacKillop</surname>
              <given-names>J</given-names>
            </name>
          </person-group>
          <article-title>Attitudes and beliefs toward cannabis before recreational legalization: a cross-sectional study of community adults in Ontario</article-title>
          <source>Cannabis Cannabinoid Res</source>
          <year>2022</year>
          <month>08</month>
          <day>01</day>
          <volume>7</volume>
          <issue>4</issue>
          <fpage>526</fpage>
          <lpage>536</lpage>
          <pub-id pub-id-type="doi">10.1089/can.2019.0088</pub-id>
          <pub-id pub-id-type="medline">33998851</pub-id>
          <pub-id pub-id-type="pmcid">PMC9418354</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref8">
        <label>8</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Kruger</surname>
              <given-names>DJ</given-names>
            </name>
            <name name-style="western">
              <surname>Kruger</surname>
              <given-names>JS</given-names>
            </name>
            <name name-style="western">
              <surname>Collins</surname>
              <given-names>RL</given-names>
            </name>
          </person-group>
          <article-title>Cannabis enthusiasts' knowledge of medical treatment effectiveness and increased risks from cannabis use</article-title>
          <source>Am J Health Promot</source>
          <year>2020</year>
          <month>05</month>
          <day>09</day>
          <volume>34</volume>
          <issue>4</issue>
          <fpage>436</fpage>
          <lpage>439</lpage>
          <pub-id pub-id-type="doi">10.1177/0890117119899218</pub-id>
          <pub-id pub-id-type="medline">31916839</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref9">
        <label>9</label>
        <nlm-citation citation-type="web">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Choi</surname>
              <given-names>NG</given-names>
            </name>
            <name name-style="western">
              <surname>DiNitto</surname>
              <given-names>DM</given-names>
            </name>
            <name name-style="western">
              <surname>Marti</surname>
              <given-names>CN</given-names>
            </name>
          </person-group>
          <article-title>Older marijuana users’ marijuana risk perceptions: associations with marijuana use patterns and marijuana and other substance use disorders</article-title>
          <source>Cambridge University Press</source>
          <year>2017</year>
          <access-date>2023-02-03</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.cambridge.org/core/journals/international-psychogeriatrics/article/abs/older-marijuana-users-marijuana-risk-perceptions-associations-with-marijuana-use-patterns-and-marijuana-and-other-substance-use-disorders/270F3C3EEDFBCF5F0C6720499AC1091D">https://tinyurl.com/2dwsysh8</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref10">
        <label>10</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>McDonald</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Hamilton</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Wickens</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Watson</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Elton-Marshall</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Wardell</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Rueda</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Roerecke</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Stoduto</surname>
              <given-names>Gina</given-names>
            </name>
            <name name-style="western">
              <surname>Mann</surname>
              <given-names>Robert E</given-names>
            </name>
          </person-group>
          <article-title>Driving under the influence of cannabis risk perceptions and behaviour: a population-based study in Ontario, Canada</article-title>
          <source>Prev Med</source>
          <year>2021</year>
          <month>12</month>
          <volume>153</volume>
          <fpage>106793</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.sciencedirect.com/science/article/pii/S0091743521003625"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.ypmed.2021.106793</pub-id>
          <pub-id pub-id-type="medline">34517043</pub-id>
          <pub-id pub-id-type="pii">S0091-7435(21)00362-5</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref11">
        <label>11</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Kosa</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Giombi</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Rains</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Cates</surname>
              <given-names>S</given-names>
            </name>
          </person-group>
          <article-title>Consumer use and understanding of labelling information on edible marijuana products sold for recreational use in the states of Colorado and Washington</article-title>
          <source>Int J Drug Policy</source>
          <year>2017</year>
          <month>05</month>
          <volume>43</volume>
          <fpage>57</fpage>
          <lpage>66</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.sciencedirect.com/science/article/pii/S0955395917300087"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.drugpo.2017.01.006</pub-id>
          <pub-id pub-id-type="medline">28222305</pub-id>
          <pub-id pub-id-type="pii">S0955-3959(17)30008-7</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref12">
        <label>12</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Hammond</surname>
              <given-names>D</given-names>
            </name>
          </person-group>
          <article-title>Communicating THC levels and 'dose' to consumers: Implications for product labelling and packaging of cannabis products in regulated markets</article-title>
          <source>Int J Drug Policy</source>
          <year>2021</year>
          <month>05</month>
          <volume>91</volume>
          <fpage>102509</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.sciencedirect.com/science/article/pii/S0955395919301823"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.drugpo.2019.07.004</pub-id>
          <pub-id pub-id-type="medline">31351756</pub-id>
          <pub-id pub-id-type="pii">S0955-3959(19)30182-3</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref13">
        <label>13</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Kruger</surname>
              <given-names>JS</given-names>
            </name>
            <name name-style="western">
              <surname>Kruger</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Collins</surname>
              <given-names>RL</given-names>
            </name>
          </person-group>
          <article-title>Knowledge and practice of harm reduction strategies among people who report frequent cannabis use</article-title>
          <source>Health Promot Pract</source>
          <year>2021</year>
          <month>01</month>
          <day>22</day>
          <volume>22</volume>
          <issue>1</issue>
          <fpage>24</fpage>
          <lpage>30</lpage>
          <pub-id pub-id-type="doi">10.1177/1524839920923999</pub-id>
          <pub-id pub-id-type="medline">32443954</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref14">
        <label>14</label>
        <nlm-citation citation-type="web">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Lubin</surname>
              <given-names>G</given-names>
            </name>
          </person-group>
          <article-title>Americans are searching for weed more than ever, according to Google</article-title>
          <source>Business Insider</source>
          <year>2016</year>
          <access-date>2023-02-03</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.businessinsider.in/Americans-are-searching-for-weed-more-than-ever-according-to-Google/articleshow/54468939.cms">https://tinyurl.com/ycr2znh6</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref15">
        <label>15</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Morahan-Martin</surname>
              <given-names>JM</given-names>
            </name>
          </person-group>
          <article-title>How internet users find, evaluate, and use online health information: a cross-cultural review</article-title>
          <source>Cyberpsychol Behav</source>
          <year>2004</year>
          <month>10</month>
          <volume>7</volume>
          <issue>5</issue>
          <fpage>497</fpage>
          <lpage>510</lpage>
          <pub-id pub-id-type="doi">10.1089/cpb.2004.7.497</pub-id>
          <pub-id pub-id-type="medline">15667044</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref16">
        <label>16</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Bonn-Miller</surname>
              <given-names>MO</given-names>
            </name>
            <name name-style="western">
              <surname>Loflin</surname>
              <given-names>MJE</given-names>
            </name>
            <name name-style="western">
              <surname>Thomas</surname>
              <given-names>BF</given-names>
            </name>
            <name name-style="western">
              <surname>Marcu</surname>
              <given-names>JP</given-names>
            </name>
            <name name-style="western">
              <surname>Hyke</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Vandrey</surname>
              <given-names>R</given-names>
            </name>
          </person-group>
          <article-title>Labeling accuracy of cannabidiol extracts sold online</article-title>
          <source>JAMA</source>
          <year>2017</year>
          <month>11</month>
          <day>07</day>
          <volume>318</volume>
          <issue>17</issue>
          <fpage>1708</fpage>
          <lpage>1709</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://europepmc.org/abstract/MED/29114823"/>
          </comment>
          <pub-id pub-id-type="doi">10.1001/jama.2017.11909</pub-id>
          <pub-id pub-id-type="medline">29114823</pub-id>
          <pub-id pub-id-type="pii">2661569</pub-id>
          <pub-id pub-id-type="pmcid">PMC5818782</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref17">
        <label>17</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Boatwright</surname>
              <given-names>KD</given-names>
            </name>
            <name name-style="western">
              <surname>Sperry</surname>
              <given-names>ML</given-names>
            </name>
          </person-group>
          <article-title>Accuracy of medical marijuana claims made by popular websites</article-title>
          <source>J Pharm Pract</source>
          <year>2020</year>
          <month>08</month>
          <day>30</day>
          <volume>33</volume>
          <issue>4</issue>
          <fpage>457</fpage>
          <lpage>464</lpage>
          <pub-id pub-id-type="doi">10.1177/0897190018818907</pub-id>
          <pub-id pub-id-type="medline">30595085</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref18">
        <label>18</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Montané</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Duran</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Capellà</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Figueras</surname>
              <given-names>A</given-names>
            </name>
          </person-group>
          <article-title>Scientific drug information in newspapers: sensationalism and low quality. The example of therapeutic use of cannabinoids</article-title>
          <source>Eur J Clin Pharmacol</source>
          <year>2005</year>
          <month>07</month>
          <day>28</day>
          <volume>61</volume>
          <issue>5-6</issue>
          <fpage>475</fpage>
          <lpage>7</lpage>
          <pub-id pub-id-type="doi">10.1007/s00228-005-0916-7</pub-id>
          <pub-id pub-id-type="medline">15983825</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref19">
        <label>19</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Halvorson</surname>
              <given-names>RT</given-names>
            </name>
            <name name-style="western">
              <surname>Stewart</surname>
              <given-names>CC</given-names>
            </name>
            <name name-style="western">
              <surname>Thakur</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Glantz</surname>
              <given-names>SA</given-names>
            </name>
          </person-group>
          <article-title>Scientific quality of health-related articles in specialty cannabis and general newspapers in San Francisco</article-title>
          <source>J Health Commun</source>
          <year>2018</year>
          <month>10</month>
          <day>25</day>
          <volume>23</volume>
          <issue>12</issue>
          <fpage>993</fpage>
          <lpage>998</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://europepmc.org/abstract/MED/30358488"/>
          </comment>
          <pub-id pub-id-type="doi">10.1080/10810730.2018.1534906</pub-id>
          <pub-id pub-id-type="medline">30358488</pub-id>
          <pub-id pub-id-type="pmcid">PMC6298831</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref20">
        <label>20</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Lau</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Gerson</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Korenstein</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Keyhani</surname>
              <given-names>S</given-names>
            </name>
          </person-group>
          <article-title>Internet claims on the health benefits of cannabis use</article-title>
          <source>J Gen Intern Med</source>
          <year>2021</year>
          <month>11</month>
          <day>19</day>
          <volume>36</volume>
          <issue>11</issue>
          <fpage>3611</fpage>
          <lpage>3614</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://europepmc.org/abstract/MED/33742301"/>
          </comment>
          <pub-id pub-id-type="doi">10.1007/s11606-020-06421-w</pub-id>
          <pub-id pub-id-type="medline">33742301</pub-id>
          <pub-id pub-id-type="pii">10.1007/s11606-020-06421-w</pub-id>
          <pub-id pub-id-type="pmcid">PMC8606495</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref21">
        <label>21</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Ng</surname>
              <given-names>JY</given-names>
            </name>
            <name name-style="western">
              <surname>Dzisiak</surname>
              <given-names>DA</given-names>
            </name>
            <name name-style="western">
              <surname>Saini</surname>
              <given-names>JB</given-names>
            </name>
          </person-group>
          <article-title>Cannabis for pain: a cross-sectional survey of the patient information quality on the Internet</article-title>
          <source>J Cannabis Res</source>
          <year>2021</year>
          <month>08</month>
          <day>16</day>
          <volume>3</volume>
          <issue>1</issue>
          <fpage>36</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://jcannabisresearch.biomedcentral.com/articles/10.1186/s42238-021-00093-x"/>
          </comment>
          <pub-id pub-id-type="doi">10.1186/s42238-021-00093-x</pub-id>
          <pub-id pub-id-type="medline">34399853</pub-id>
          <pub-id pub-id-type="pii">10.1186/s42238-021-00093-x</pub-id>
          <pub-id pub-id-type="pmcid">PMC8369629</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref22">
        <label>22</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Premkumar</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Almeida</surname>
              <given-names>BA</given-names>
            </name>
            <name name-style="western">
              <surname>Lopez</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Pean</surname>
              <given-names>CA</given-names>
            </name>
            <name name-style="western">
              <surname>Nwachukwu</surname>
              <given-names>BU</given-names>
            </name>
            <name name-style="western">
              <surname>Sculco</surname>
              <given-names>PK</given-names>
            </name>
          </person-group>
          <article-title>The quality of online resources available to patients regarding cannabidiol for symptomatic relief of hip or knee arthritis is poor</article-title>
          <source>J Am Acad Orthop Surg Glob Res Rev</source>
          <year>2021</year>
          <month>01</month>
          <day>22</day>
          <volume>5</volume>
          <issue>1</issue>
          <fpage>1</fpage>
          <lpage>7</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://journals.lww.com/jaaosglobal/Fulltext/2021/01000/The_Quality_of_Online_Resources_Available_to.9.aspx?context=LatestArticles"/>
          </comment>
          <pub-id pub-id-type="doi">10.5435/JAAOSGlobal-D-20-00241</pub-id>
          <pub-id pub-id-type="medline">33497073</pub-id>
          <pub-id pub-id-type="pii">01979360-202101000-00009</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref23">
        <label>23</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Lamy</surname>
              <given-names>F</given-names>
            </name>
            <name name-style="western">
              <surname>Daniulaityte</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Zatreh</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Nahhas</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Sheth</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Martins</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Boyer</surname>
              <given-names>EW</given-names>
            </name>
            <name name-style="western">
              <surname>Carlson</surname>
              <given-names>RG</given-names>
            </name>
          </person-group>
          <article-title>"You got to love rosin: Solventless dabs, pure, clean, natural medicine." Exploring Twitter data on emerging trends in Rosin Tech marijuana concentrates</article-title>
          <source>Drug Alcohol Depend</source>
          <year>2018</year>
          <month>03</month>
          <day>01</day>
          <volume>183</volume>
          <fpage>248</fpage>
          <lpage>252</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://europepmc.org/abstract/MED/29306816"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.drugalcdep.2017.10.039</pub-id>
          <pub-id pub-id-type="medline">29306816</pub-id>
          <pub-id pub-id-type="pii">S0376-8716(17)30604-X</pub-id>
          <pub-id pub-id-type="pmcid">PMC5803369</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref24">
        <label>24</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Merten</surname>
              <given-names>JW</given-names>
            </name>
            <name name-style="western">
              <surname>Gordon</surname>
              <given-names>BT</given-names>
            </name>
            <name name-style="western">
              <surname>King</surname>
              <given-names>JL</given-names>
            </name>
            <name name-style="western">
              <surname>Pappas</surname>
              <given-names>C</given-names>
            </name>
          </person-group>
          <article-title>Cannabidiol (CBD): perspectives from Pinterest</article-title>
          <source>Subst Use Misuse</source>
          <year>2020</year>
          <month>07</month>
          <day>25</day>
          <volume>55</volume>
          <issue>13</issue>
          <fpage>2213</fpage>
          <lpage>2220</lpage>
          <pub-id pub-id-type="doi">10.1080/10826084.2020.1797808</pub-id>
          <pub-id pub-id-type="medline">32715862</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref25">
        <label>25</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Ramo</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Popova</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Grana</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Zhao</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Chavez</surname>
              <given-names>K</given-names>
            </name>
          </person-group>
          <article-title>Cannabis mobile apps: a content analysis</article-title>
          <source>JMIR Mhealth Uhealth</source>
          <year>2015</year>
          <month>08</month>
          <day>12</day>
          <volume>3</volume>
          <issue>3</issue>
          <fpage>e81</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://mhealth.jmir.org/2015/3/e81/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/mhealth.4405</pub-id>
          <pub-id pub-id-type="medline">26268634</pub-id>
          <pub-id pub-id-type="pii">v3i3e81</pub-id>
          <pub-id pub-id-type="pmcid">PMC4705020</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref26">
        <label>26</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Ouellette</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Cearley</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Judge</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Riley</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Jones</surname>
              <given-names>J</given-names>
            </name>
          </person-group>
          <article-title>Cooking with cannabis: The rapid spread of (mis)information on YouTube</article-title>
          <source>Am J Emerg Med</source>
          <year>2018</year>
          <month>07</month>
          <volume>36</volume>
          <issue>7</issue>
          <fpage>1300</fpage>
          <lpage>1301</lpage>
          <pub-id pub-id-type="doi">10.1016/j.ajem.2017.10.060</pub-id>
          <pub-id pub-id-type="medline">29096918</pub-id>
          <pub-id pub-id-type="pii">S0735-6757(17)30888-4</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref27">
        <label>27</label>
        <nlm-citation citation-type="book">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Edberg</surname>
              <given-names>M</given-names>
            </name>
          </person-group>
          <source>Essential Readings in Health Behavior: Theory and Practice</source>
          <year>2010</year>
          <publisher-loc>Sudbury, MA</publisher-loc>
          <publisher-name>Jones &amp; Bartlett Learning</publisher-name>
          <fpage>321</fpage>
        </nlm-citation>
      </ref>
      <ref id="ref28">
        <label>28</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Swift</surname>
              <given-names>W</given-names>
            </name>
            <name name-style="western">
              <surname>Copeland</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Lenton</surname>
              <given-names>S</given-names>
            </name>
          </person-group>
          <article-title>Cannabis and harm reduction</article-title>
          <source>Drug Alcohol Rev Internet</source>
          <year>2000</year>
          <volume>19</volume>
          <issue>1</issue>
          <fpage>101</fpage>
          <lpage>112</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.tandfonline.com/doi/abs/10.1080/09595230096200"/>
          </comment>
          <pub-id pub-id-type="doi">10.1080/09595230096200</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref29">
        <label>29</label>
        <nlm-citation citation-type="web">
          <article-title>Search engine market share Canada</article-title>
          <source>Statcounter</source>
          <access-date>2021-07-18</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://gs.statcounter.com/search-engine-market-share/all/canada">https://gs.statcounter.com/search-engine-market-share/all/canada</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref30">
        <label>30</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Schultheiß</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Lewandowski</surname>
              <given-names>D</given-names>
            </name>
          </person-group>
          <article-title>Misplaced trust? The relationship between trust, ability to identify commercially influenced results and search engine preference</article-title>
          <source>J Inf Sci</source>
          <year>2021</year>
          <month>05</month>
          <day>14</day>
          <pub-id pub-id-type="doi">10.1177/01655515211014157</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref31">
        <label>31</label>
        <nlm-citation citation-type="book">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>King</surname>
              <given-names>A</given-names>
            </name>
          </person-group>
          <source>Website Optimization</source>
          <year>2008</year>
          <month>07</month>
          <publisher-loc>Sebastopol, CA</publisher-loc>
          <publisher-name>O'Reilly Media Inc</publisher-name>
        </nlm-citation>
      </ref>
      <ref id="ref32">
        <label>32</label>
        <nlm-citation citation-type="web">
          <source>Google</source>
          <access-date>2023-03-30</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.google.ca/">https://www.google.ca/</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref33">
        <label>33</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Schwarzbach</surname>
              <given-names>HL</given-names>
            </name>
            <name name-style="western">
              <surname>Mady</surname>
              <given-names>LJ</given-names>
            </name>
            <name name-style="western">
              <surname>Kaffenberger</surname>
              <given-names>TM</given-names>
            </name>
            <name name-style="western">
              <surname>Duvvuri</surname>
              <given-names>U</given-names>
            </name>
            <name name-style="western">
              <surname>Jabbour</surname>
              <given-names>N</given-names>
            </name>
          </person-group>
          <article-title>Quality and readability assessment of websites on human papillomavirus and oropharyngeal cancer</article-title>
          <source>Laryngoscope</source>
          <year>2021</year>
          <month>01</month>
          <day>13</day>
          <volume>131</volume>
          <issue>1</issue>
          <fpage>87</fpage>
          <lpage>94</lpage>
          <pub-id pub-id-type="doi">10.1002/lary.28670</pub-id>
          <pub-id pub-id-type="medline">32282087</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref34">
        <label>34</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Safdari</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Gholamzadeh</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Saeedi</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Tanhapour</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Rezayi</surname>
              <given-names>S</given-names>
            </name>
          </person-group>
          <article-title>An evaluation of the quality of COVID-19 websites in terms of HON principles and using DISCERN tool</article-title>
          <source>Health Info Libr J</source>
          <year>2022</year>
          <month>08</month>
          <day>10</day>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://europepmc.org/abstract/MED/35949046"/>
          </comment>
          <pub-id pub-id-type="doi">10.1111/hir.12454</pub-id>
          <pub-id pub-id-type="medline">35949046</pub-id>
          <pub-id pub-id-type="pmcid">PMC9539229</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref35">
        <label>35</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>St John</surname>
              <given-names>Ace</given-names>
            </name>
            <name name-style="western">
              <surname>Carlisle</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Kligman</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Kavic</surname>
              <given-names>SM</given-names>
            </name>
          </person-group>
          <article-title>What's Nissen on the net? the quality of information regarding Nissen fundoplication on the internet</article-title>
          <source>Surg Endosc</source>
          <year>2022</year>
          <month>07</month>
          <day>29</day>
          <volume>36</volume>
          <issue>7</issue>
          <fpage>5198</fpage>
          <lpage>5206</lpage>
          <pub-id pub-id-type="doi">10.1007/s00464-021-08895-z</pub-id>
          <pub-id pub-id-type="medline">34845552</pub-id>
          <pub-id pub-id-type="pii">10.1007/s00464-021-08895-z</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref36">
        <label>36</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Flint</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Inglis</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Hill</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Mair</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Hatrick</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Tacchi</surname>
              <given-names>MJ</given-names>
            </name>
            <name name-style="western">
              <surname>Scott</surname>
              <given-names>J</given-names>
            </name>
          </person-group>
          <article-title>A comparative study of strategies for identifying credible sources of mental health information online: Can clinical services deliver a youth-specific internet prescription?</article-title>
          <source>Early Interv Psychiatry</source>
          <year>2022</year>
          <month>06</month>
          <day>02</day>
          <volume>16</volume>
          <issue>6</issue>
          <fpage>643</fpage>
          <lpage>650</lpage>
          <pub-id pub-id-type="doi">10.1111/eip.13209</pub-id>
          <pub-id pub-id-type="medline">34474508</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref37">
        <label>37</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Jasem</surname>
              <given-names>Z</given-names>
            </name>
            <name name-style="western">
              <surname>AlMeraj</surname>
              <given-names>Z</given-names>
            </name>
            <name name-style="western">
              <surname>Alhuwail</surname>
              <given-names>D</given-names>
            </name>
          </person-group>
          <article-title>Evaluating breast cancer websites targeting Arabic speakers: empirical investigation of popularity, availability, accessibility, readability, and quality</article-title>
          <source>BMC Med Inform Decis Mak</source>
          <year>2022</year>
          <month>05</month>
          <day>09</day>
          <volume>22</volume>
          <issue>1</issue>
          <fpage>126</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://bmcmedinformdecismak.biomedcentral.com/articles/10.1186/s12911-022-01868-9"/>
          </comment>
          <pub-id pub-id-type="doi">10.1186/s12911-022-01868-9</pub-id>
          <pub-id pub-id-type="medline">35534816</pub-id>
          <pub-id pub-id-type="pii">10.1186/s12911-022-01868-9</pub-id>
          <pub-id pub-id-type="pmcid">PMC9082957</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref38">
        <label>38</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Smekal</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Gil</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Donald</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Beanlands</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Straus</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Herrington</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Sparkes</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Harwood</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Tong</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Grill</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Tu</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Waldvogel</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Large</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Large</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Novak</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>James</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Elliott</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Delgado</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Brimble</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Samuel</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Hemmelgarn</surname>
              <given-names>BR</given-names>
            </name>
          </person-group>
          <article-title>Content and quality of websites for patients with chronic kidney disease: an environmental scan</article-title>
          <source>Can J Kidney Health Dis</source>
          <year>2019</year>
          <month>07</month>
          <day>30</day>
          <volume>6</volume>
          <fpage>2054358119863091</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://journals.sagepub.com/doi/10.1177/2054358119863091?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub  0pubmed"/>
          </comment>
          <pub-id pub-id-type="doi">10.1177/2054358119863091</pub-id>
          <pub-id pub-id-type="medline">31391944</pub-id>
          <pub-id pub-id-type="pii">10.1177_2054358119863091</pub-id>
          <pub-id pub-id-type="pmcid">PMC6668187</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref39">
        <label>39</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Boyer</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Baujard</surname>
              <given-names>V</given-names>
            </name>
            <name name-style="western">
              <surname>Geissbuhler</surname>
              <given-names>A</given-names>
            </name>
          </person-group>
          <article-title>Evolution of health web certification through the HONcode experience</article-title>
          <source>Stud Health Technol Inform</source>
          <year>2011</year>
          <volume>169</volume>
          <fpage>53</fpage>
          <lpage>57</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://archive-ouverte.unige.ch/unige:25557"/>
          </comment>
          <pub-id pub-id-type="doi">10.4414/smi.26.00233</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref40">
        <label>40</label>
        <nlm-citation citation-type="web">
          <article-title>HONcode certification</article-title>
          <source>Health On the Net</source>
          <access-date>2023-02-03</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.hon.ch/en/certification.html">https://www.hon.ch/en/certification.html</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref41">
        <label>41</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Robillard</surname>
              <given-names>JM</given-names>
            </name>
            <name name-style="western">
              <surname>Jun</surname>
              <given-names>JH</given-names>
            </name>
            <name name-style="western">
              <surname>Lai</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Feng</surname>
              <given-names>TL</given-names>
            </name>
          </person-group>
          <article-title>The QUEST for quality online health information: validation of a short quantitative tool</article-title>
          <source>BMC Med Inform Decis Mak</source>
          <year>2018</year>
          <month>10</month>
          <day>19</day>
          <volume>18</volume>
          <issue>1</issue>
          <fpage>87</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://bmcmedinformdecismak.biomedcentral.com/articles/10.1186/s12911-018-0668-9"/>
          </comment>
          <pub-id pub-id-type="doi">10.1186/s12911-018-0668-9</pub-id>
          <pub-id pub-id-type="medline">30340488</pub-id>
          <pub-id pub-id-type="pii">10.1186/s12911-018-0668-9</pub-id>
          <pub-id pub-id-type="pmcid">PMC6194721</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref42">
        <label>42</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Lenaerts</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Bekkering</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Goossens</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>De Coninck</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Delvaux</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Cordyn</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Adriaenssens</surname>
              <given-names>Jef</given-names>
            </name>
            <name name-style="western">
              <surname>Vankrunkelsven</surname>
              <given-names>Patrick</given-names>
            </name>
          </person-group>
          <article-title>Tools to assess the trustworthiness of evidence-based point-of-care information for health care professionals: systematic review</article-title>
          <source>J Med Internet Res</source>
          <year>2020</year>
          <month>01</month>
          <day>17</day>
          <volume>22</volume>
          <issue>1</issue>
          <fpage>e15415</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.jmir.org/2020/1/e15415/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/15415</pub-id>
          <pub-id pub-id-type="medline">31951213</pub-id>
          <pub-id pub-id-type="pii">v22i1e15415</pub-id>
          <pub-id pub-id-type="pmcid">PMC6996752</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref43">
        <label>43</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Chen</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Gentry</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Qiu</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Deng</surname>
              <given-names>Y</given-names>
            </name>
            <name name-style="western">
              <surname>Notley</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Cheng</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Song</surname>
              <given-names>Fujian</given-names>
            </name>
          </person-group>
          <article-title>Online information on electronic cigarettes: comparative study of relevant websites from Baidu and google search engines</article-title>
          <source>J Med Internet Res</source>
          <year>2020</year>
          <month>01</month>
          <day>24</day>
          <volume>22</volume>
          <issue>1</issue>
          <fpage>e14725</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.jmir.org/2020/1/e14725/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/14725</pub-id>
          <pub-id pub-id-type="medline">32012069</pub-id>
          <pub-id pub-id-type="pii">v22i1e14725</pub-id>
          <pub-id pub-id-type="pmcid">PMC7007591</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref44">
        <label>44</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Bachu</surname>
              <given-names>V</given-names>
            </name>
            <name name-style="western">
              <surname>Mahjoub</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Holler</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Crihalmeanu</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Bachu</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Ayyaswami</surname>
              <given-names>V</given-names>
            </name>
            <name name-style="western">
              <surname>Parker</surname>
              <given-names>PD</given-names>
            </name>
            <name name-style="western">
              <surname>Prabhu</surname>
              <given-names>A</given-names>
            </name>
          </person-group>
          <article-title>Assessing COVID-19 health information on Google using the Quality Evaluation Scoring Tool (QUEST): cross-sectional and readability analysis</article-title>
          <source>JMIR Form Res</source>
          <year>2022</year>
          <month>03</month>
          <day>11</day>
          <volume>6</volume>
          <issue>2</issue>
          <fpage>e32443</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://formative.jmir.org/2022/2/e32443/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/32443</pub-id>
          <pub-id pub-id-type="medline">34995206</pub-id>
          <pub-id pub-id-type="pii">v6i2e32443</pub-id>
          <pub-id pub-id-type="pmcid">PMC8843082</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref45">
        <label>45</label>
        <nlm-citation citation-type="web">
          <article-title>Attribution 4.0 International (CC BY 4.0)</article-title>
          <source>Creative Commons</source>
          <access-date>2023-04-25</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://creativecommons.org/licenses/by/4.0/">https://creativecommons.org/licenses/by/4.0/</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref46">
        <label>46</label>
        <nlm-citation citation-type="web">
          <source>Readability Formulas</source>
          <access-date>2023-02-03</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://readabilityformulas.com/">https://readabilityformulas.com/</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref47">
        <label>47</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Worrall</surname>
              <given-names>AP</given-names>
            </name>
            <name name-style="western">
              <surname>Connolly</surname>
              <given-names>MJ</given-names>
            </name>
            <name name-style="western">
              <surname>O'Neill</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>O'Doherty</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Thornton</surname>
              <given-names>KP</given-names>
            </name>
            <name name-style="western">
              <surname>McNally</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>McConkey</surname>
              <given-names>SJ</given-names>
            </name>
            <name name-style="western">
              <surname>de Barra</surname>
              <given-names>E</given-names>
            </name>
          </person-group>
          <article-title>Readability of online COVID-19 health information: a comparison between four English speaking countries</article-title>
          <source>BMC Public Health</source>
          <year>2020</year>
          <month>11</month>
          <day>13</day>
          <volume>20</volume>
          <issue>1</issue>
          <fpage>1635</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://bmcpublichealth.biomedcentral.com/articles/10.1186/s12889-020-09710-5"/>
          </comment>
          <pub-id pub-id-type="doi">10.1186/s12889-020-09710-5</pub-id>
          <pub-id pub-id-type="medline">33183297</pub-id>
          <pub-id pub-id-type="pii">10.1186/s12889-020-09710-5</pub-id>
          <pub-id pub-id-type="pmcid">PMC7661100</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref48">
        <label>48</label>
        <nlm-citation citation-type="web">
          <source>Readable</source>
          <access-date>2023-02-03</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://app.readable.com/text/">https://app.readable.com/text/</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref49">
        <label>49</label>
        <nlm-citation citation-type="web">
          <article-title>The Gunning Fog Index</article-title>
          <source>Readable</source>
          <access-date>2023-02-03</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://readable.com/readability/gunning-fog-index/">https://readable.com/readability/gunning-fog-index/</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref50">
        <label>50</label>
        <nlm-citation citation-type="web">
          <article-title>Flesch Reading Ease and the Flesch Kincaid Grade Level</article-title>
          <source>Readable</source>
          <access-date>2022-02-03</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://readable.com/readability/flesch-reading-ease-flesch-kincaid-grade-level/">https://readable.com/readability/flesch-reading-ease-flesch-kincaid-grade-level/</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref51">
        <label>51</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Roberts</surname>
              <given-names>L</given-names>
            </name>
          </person-group>
          <article-title>Health information and the Internet: The 5 Cs website evaluation tool</article-title>
          <source>Br J Nurs</source>
          <year>2010</year>
          <month>03</month>
          <day>12</day>
          <volume>19</volume>
          <issue>5</issue>
          <fpage>322</fpage>
          <lpage>5</lpage>
          <pub-id pub-id-type="doi">10.12968/bjon.2010.19.5.47075</pub-id>
          <pub-id pub-id-type="medline">20335904</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref52">
        <label>52</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Alshaikh</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Shimozono</surname>
              <given-names>Y</given-names>
            </name>
            <name name-style="western">
              <surname>Dankert</surname>
              <given-names>JF</given-names>
            </name>
            <name name-style="western">
              <surname>Ubillus</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Kennedy</surname>
              <given-names>JG</given-names>
            </name>
          </person-group>
          <article-title>Evaluation of the quality and readability of online sources on the diagnosis and management of osteochondral lesions of the ankle</article-title>
          <source>Cartilage</source>
          <year>2021</year>
          <month>12</month>
          <day>10</day>
          <volume>13</volume>
          <issue>1_suppl</issue>
          <fpage>1422S</fpage>
          <lpage>1428S</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://europepmc.org/abstract/MED/34109846"/>
          </comment>
          <pub-id pub-id-type="doi">10.1177/19476035211021910</pub-id>
          <pub-id pub-id-type="medline">34109846</pub-id>
          <pub-id pub-id-type="pmcid">PMC8808952</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref53">
        <label>53</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Hungerford</surname>
              <given-names>D</given-names>
            </name>
          </person-group>
          <article-title>Internet access produces misinformed patients: managing the confusion</article-title>
          <source>Orthopedics</source>
          <year>2009</year>
          <month>10</month>
          <volume>32</volume>
          <issue>9</issue>
          <fpage>658</fpage>
          <lpage>660</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.proquest.com/docview/220387934/abstract/B7AA93AA0B4E4F88PQ/1"/>
          </comment>
          <pub-id pub-id-type="doi">10.3928/01477447-20090728-04</pub-id>
          <pub-id pub-id-type="medline">19751023</pub-id>
          <pub-id pub-id-type="pii">orthopedics.42830</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref54">
        <label>54</label>
        <nlm-citation citation-type="web">
          <article-title>Government information: evaluating sources/how to read a scholarly article</article-title>
          <source>LibGuides: Wells College</source>
          <access-date>2023-02-03</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://libguides.wells.edu/c.php?g=239219&amp;p=1590822">https://libguides.wells.edu/c.php?g=239219&amp;p=1590822</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref55">
        <label>55</label>
        <nlm-citation citation-type="web">
          <article-title>Using sources: evaluating sources and avoiding plagiarism</article-title>
          <source>LibGuides: Northern Virginia Community College</source>
          <access-date>2023-02-03</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://libguides.nvcc.edu/c.php?g=361391&amp;p=2440252">https://libguides.nvcc.edu/c.php?g=361391&amp;p=2440252</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref56">
        <label>56</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Ramli</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Jambor</surname>
              <given-names>MA</given-names>
            </name>
            <name name-style="western">
              <surname>Kong</surname>
              <given-names>CY</given-names>
            </name>
          </person-group>
          <article-title>Dr Google - assessing the reliability and readability of information on general surgical procedures found via search engines</article-title>
          <source>ANZ J Surg</source>
          <year>2023</year>
          <month>03</month>
          <day>30</day>
          <volume>93</volume>
          <issue>3</issue>
          <fpage>590</fpage>
          <lpage>596</lpage>
          <pub-id pub-id-type="doi">10.1111/ans.18289</pub-id>
          <pub-id pub-id-type="medline">36716246</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref57">
        <label>57</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Karimi</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Shah</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Hecht</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Burkhart</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Acuña</surname>
              <given-names>AJ</given-names>
            </name>
            <name name-style="western">
              <surname>Kamath</surname>
              <given-names>A</given-names>
            </name>
          </person-group>
          <article-title>Readability of online patient education materials for total joint arthroplasty: a systematic review</article-title>
          <source>J Arthroplasty</source>
          <year>2023</year>
          <month>01</month>
          <day>27</day>
          <fpage>A</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.sciencedirect.com/science/article/pii/S0883540323000529"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.arth.2023.01.032</pub-id>
          <pub-id pub-id-type="medline">36716898</pub-id>
          <pub-id pub-id-type="pii">S0883-5403(23)00052-9</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref58">
        <label>58</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Kruger</surname>
              <given-names>DJ</given-names>
            </name>
            <name name-style="western">
              <surname>Moffet</surname>
              <given-names>IM</given-names>
            </name>
            <name name-style="western">
              <surname>Seluk</surname>
              <given-names>LC</given-names>
            </name>
            <name name-style="western">
              <surname>Zammit</surname>
              <given-names>LA</given-names>
            </name>
          </person-group>
          <article-title>A content analysis of internet information sources on medical cannabis</article-title>
          <source>J Cannabis Res</source>
          <year>2020</year>
          <month>09</month>
          <day>18</day>
          <volume>2</volume>
          <issue>1</issue>
          <fpage>29</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://jcannabisresearch.biomedcentral.com/articles/10.1186/s42238-020-00041-1"/>
          </comment>
          <pub-id pub-id-type="doi">10.1186/s42238-020-00041-1</pub-id>
          <pub-id pub-id-type="medline">33526127</pub-id>
          <pub-id pub-id-type="pii">10.1186/s42238-020-00041-1</pub-id>
          <pub-id pub-id-type="pmcid">PMC7819301</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref59">
        <label>59</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Gordon</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Crouch</surname>
              <given-names>E</given-names>
            </name>
          </person-group>
          <article-title>Digital information technology use and patient preferences for internet-based health education modalities: cross-sectional survey study of middle-aged and older adults with chronic health conditions</article-title>
          <source>JMIR Aging</source>
          <year>2019</year>
          <month>04</month>
          <day>04</day>
          <volume>2</volume>
          <issue>1</issue>
          <fpage>e12243</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://aging.jmir.org/2019/1/e12243/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/12243</pub-id>
          <pub-id pub-id-type="medline">31518291</pub-id>
          <pub-id pub-id-type="pii">v2i1e12243</pub-id>
          <pub-id pub-id-type="pmcid">PMC6716442</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref60">
        <label>60</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Ishida</surname>
              <given-names>JH</given-names>
            </name>
            <name name-style="western">
              <surname>Zhang</surname>
              <given-names>AJ</given-names>
            </name>
            <name name-style="western">
              <surname>Steigerwald</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Cohen</surname>
              <given-names>BE</given-names>
            </name>
            <name name-style="western">
              <surname>Vali</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Keyhani</surname>
              <given-names>S</given-names>
            </name>
          </person-group>
          <article-title>Sources of information and beliefs about the health effects of marijuana</article-title>
          <source>J Gen Intern Med</source>
          <year>2020</year>
          <month>01</month>
          <day>21</day>
          <volume>35</volume>
          <issue>1</issue>
          <fpage>153</fpage>
          <lpage>159</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://europepmc.org/abstract/MED/31637640"/>
          </comment>
          <pub-id pub-id-type="doi">10.1007/s11606-019-05335-6</pub-id>
          <pub-id pub-id-type="medline">31637640</pub-id>
          <pub-id pub-id-type="pii">10.1007/s11606-019-05335-6</pub-id>
          <pub-id pub-id-type="pmcid">PMC6957653</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref61">
        <label>61</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>AlGhamdi</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Moussa</surname>
              <given-names>N</given-names>
            </name>
          </person-group>
          <article-title>Internet use by the public to search for health-related information</article-title>
          <source>Int J Med Inform</source>
          <year>2012</year>
          <month>06</month>
          <volume>81</volume>
          <issue>6</issue>
          <fpage>363</fpage>
          <lpage>73</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.sciencedirect.com/science/article/pii/S1386505611002644"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.ijmedinf.2011.12.004</pub-id>
          <pub-id pub-id-type="medline">22217800</pub-id>
          <pub-id pub-id-type="pii">S1386-5056(11)00264-4</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref62">
        <label>62</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Azofeifa</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Mattson</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Schauer</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>McAfee</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Grant</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Lyerla</surname>
              <given-names>R</given-names>
            </name>
          </person-group>
          <article-title>National estimates of marijuana use and related indicators - national survey on drug use and health, United States, 2002-2014</article-title>
          <source>MMWR Surveill Summ</source>
          <year>2016</year>
          <month>10</month>
          <day>02</day>
          <volume>65</volume>
          <issue>11</issue>
          <fpage>1</fpage>
          <lpage>28</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.jstor.org/stable/24805822"/>
          </comment>
          <pub-id pub-id-type="doi">10.15585/mmwr.ss6511a1</pub-id>
          <pub-id pub-id-type="medline">27584586</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref63">
        <label>63</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Berg</surname>
              <given-names>CJ</given-names>
            </name>
            <name name-style="western">
              <surname>Daniel</surname>
              <given-names>CN</given-names>
            </name>
            <name name-style="western">
              <surname>Vu</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Li</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Martin</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Le</surname>
              <given-names>L</given-names>
            </name>
          </person-group>
          <article-title>Marijuana use and driving under the influence among young adults: a socioecological perspective on risk factors</article-title>
          <source>Subst Use Misuse</source>
          <year>2018</year>
          <month>03</month>
          <day>23</day>
          <volume>53</volume>
          <issue>3</issue>
          <fpage>370</fpage>
          <lpage>380</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://europepmc.org/abstract/MED/28777692"/>
          </comment>
          <pub-id pub-id-type="doi">10.1080/10826084.2017.1327979</pub-id>
          <pub-id pub-id-type="medline">28777692</pub-id>
          <pub-id pub-id-type="pmcid">PMC6088242</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref64">
        <label>64</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Lenné</surname>
              <given-names>MG</given-names>
            </name>
            <name name-style="western">
              <surname>Dietze</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Triggs</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Walmsley</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Murphy</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Redman</surname>
              <given-names>J</given-names>
            </name>
          </person-group>
          <article-title>The effects of cannabis and alcohol on simulated arterial driving: Influences of driving experience and task demand</article-title>
          <source>Accid Anal Prev</source>
          <year>2010</year>
          <month>05</month>
          <volume>42</volume>
          <issue>3</issue>
          <fpage>859</fpage>
          <lpage>66</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.sciencedirect.com/science/article/pii/S0001457509000918"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.aap.2009.04.021</pub-id>
          <pub-id pub-id-type="medline">20380913</pub-id>
          <pub-id pub-id-type="pii">S0001-4575(09)00091-8</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref65">
        <label>65</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Hartman</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Huestis</surname>
              <given-names>M</given-names>
            </name>
          </person-group>
          <article-title>Cannabis effects on driving skills</article-title>
          <source>Clin Chem</source>
          <year>2013</year>
          <month>03</month>
          <volume>59</volume>
          <issue>3</issue>
          <fpage>478</fpage>
          <lpage>92</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://europepmc.org/abstract/MED/23220273"/>
          </comment>
          <pub-id pub-id-type="doi">10.1373/clinchem.2012.194381</pub-id>
          <pub-id pub-id-type="medline">23220273</pub-id>
          <pub-id pub-id-type="pii">clinchem.2012.194381</pub-id>
          <pub-id pub-id-type="pmcid">PMC3836260</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref66">
        <label>66</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Li</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Brady</surname>
              <given-names>JE</given-names>
            </name>
            <name name-style="western">
              <surname>DiMaggio</surname>
              <given-names>CJ</given-names>
            </name>
            <name name-style="western">
              <surname>Lusardi</surname>
              <given-names>AR</given-names>
            </name>
            <name name-style="western">
              <surname>Tzong</surname>
              <given-names>KY</given-names>
            </name>
            <name name-style="western">
              <surname>Li</surname>
              <given-names>G</given-names>
            </name>
          </person-group>
          <article-title>Marijuana use and motor vehicle crashes</article-title>
          <source>Epidemiol Rev</source>
          <year>2012</year>
          <month>10</month>
          <day>04</day>
          <volume>34</volume>
          <issue>1</issue>
          <fpage>65</fpage>
          <lpage>72</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://europepmc.org/abstract/MED/21976636"/>
          </comment>
          <pub-id pub-id-type="doi">10.1093/epirev/mxr017</pub-id>
          <pub-id pub-id-type="medline">21976636</pub-id>
          <pub-id pub-id-type="pii">mxr017</pub-id>
          <pub-id pub-id-type="pmcid">PMC3276316</pub-id>
        </nlm-citation>
      </ref>
    </ref-list>
  </back>
</article>
